Fmoc-N-Me-Phe-OH
Fmoc-N-Me-Phe-OH (CAS 77128-73-5), a derivative of phenylalanine, is a crucial N-methylated amino acid with the molecular formula C25H23NO4 and a molecular weight of 401.45 g/mol. Its unique structure makes it valuable in peptide chemistry and chemical synthesis. This compound is primarily used as a building block in the creation of modified peptides and in research applications within chemical biology.
- IUPAC
- Fmoc-N-methyl-L-phenylalanine
Peptide Synthesis
Fmoc-N-Me-Phe-OH serves as a key building block in the solid-phase synthesis of peptides, enabling the incorporation of N-methylated phenylalanine residues. This modification can alter peptide conformation, stability, and biological activity.
Chemical Biology Research
Utilized in chemical biology, this compound aids in the study of protein structure-function relationships and the development of novel biologically active molecules. Its incorporation can lead to peptides with enhanced receptor binding or altered enzymatic properties.
Drug Discovery and Development
As an unnatural amino acid derivative, Fmoc-N-Me-Phe-OH is employed in medicinal chemistry for the design and synthesis of peptidomimetics and small molecule therapeutics. It can contribute to improved pharmacokinetic profiles or target specificity.
Analytical Standards
The compound may be used as an analytical standard or reference material in chromatography and other analytical techniques, particularly in the quality control of synthetic peptides or related pharmaceutical intermediates.
| Molecular weight | 401.45 |
|---|---|
| Empirical formula | C25H23NO4 |
| Assay | ≥99.0% (sum of enantiomers, HPLC) |
| Optical activity | [α]20/D −55.0±3°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-N-Me-Phe-OH used for?
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Fmoc-N-Me-Phe-OH is primarily used as a building block in peptide synthesis, particularly for creating modified peptides with altered properties. It is also employed in chemical biology research and drug discovery for the development of novel molecules.
What are the CAS number and formula for Fmoc-N-Me-Phe-OH?
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The CAS number for Fmoc-N-Me-Phe-OH is 77128-73-5, and its empirical formula is C25H23NO4.
What grade and purity does Tech Serve Solutions supply for Fmoc-N-Me-Phe-OH?
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Tech Serve Solutions supplies Fmoc-N-Me-Phe-OH with an assay of ≥99.0% (sum of enantiomers, HPLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should Fmoc-N-Me-Phe-OH be handled and stored?
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Fmoc-N-Me-Phe-OH should be stored at 2-8°C. When handling, ensure appropriate personal protective equipment is used, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound has a WGK Germany rating of 3.
Is Fmoc-N-Me-Phe-OH a controlled substance?
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The provided data does not indicate that Fmoc-N-Me-Phe-OH is a controlled substance.
How is Fmoc-N-Me-Phe-OH shipped and exported by TSS?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, capable of handling and exporting compounds like Fmoc-N-Me-Phe-OH.
How can I request a quote or sample for Fmoc-N-Me-Phe-OH?
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Please contact Tech Serve Solutions directly through our website or sales representatives to request a quote or sample for Fmoc-N-Me-Phe-OH.
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