Fmoc-Gly-Bt
Fmoc-Gly-Bt (CAS: 1082989-49-8, C23H18N4O3) is a benzotriazole amino acid derivative with a molecular weight of 398.41. This compound serves as a valuable reagent in chemical synthesis, particularly for the construction of peptides, peptidomimetics, and various peptide conjugates. Its utility extends to applications in chemical biology and peptide chemistry, facilitating the creation of complex biomolecules.
- IUPAC
- 9H-Fluoren-9-yl)methyl 2-(1H-benzo[d][1,2,3]triazol-1-yl)-2-oxoethylcarbamate,N-Fmoc-(1-benzotriazolylcarbonyl)methylamine
Peptide Synthesis
Fmoc-Gly-Bt is employed in solid-phase and solution-phase peptide synthesis strategies. It acts as an activated glycine building block, allowing for efficient coupling reactions during peptide chain elongation.
Peptidomimetic and Conjugate Preparation
This reagent facilitates the synthesis of modified peptides, including peptidomimetics, and can be used to create peptide conjugates by linking to various molecules or labels.
Chemical Biology Research
In chemical biology, Fmoc-Gly-Bt aids in the development of novel probes, modified peptides, and complex molecular architectures for studying biological processes.
| Molecular weight | 398.41 |
|---|---|
| Empirical formula | C23H18N4O3 |
| Assay | 97% |
| Storage temperature | −20°C |
| Application | Benzotriazole amino acids, or aminoacylbenzotriazolides, are versatile reagents for synthesizing peptides as well as their mimetics and conjugates. Benzotriazole amino acids have been used for the preparation of diverse derivatives including:• Polypeptidal benzotriazolides1• Peptidomimetics, such as aminoxypeptides2, depsipeptides3 and heterocyclic peptidomimetics4• Tagged peptides and peptidomimetics, particularly those with fluorescent labels5,6• N, O, S, and C linked peptide conjugates6 |
| Melting point | 160-168 °C |
Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Gly-Bt used for?
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Fmoc-Gly-Bt is used as a reagent for synthesizing peptides, peptidomimetics, and peptide conjugates, finding applications in peptide chemistry and chemical biology.
What is the CAS number and formula for Fmoc-Gly-Bt?
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The CAS number for Fmoc-Gly-Bt is 1082989-49-8, and its molecular formula is C23H18N4O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Gly-Bt with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should Fmoc-Gly-Bt be handled and stored?
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Fmoc-Gly-Bt is classified as harmful if swallowed (H302). It should be handled with appropriate personal protective equipment in a well-ventilated area and stored at -20°C.
Does TSS export Fmoc-Gly-Bt?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Fmoc-Gly-Bt.
How can I request a quote or sample for Fmoc-Gly-Bt?
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To request a quote or sample, please contact our sales team through the website or by phone.
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