Ethyl trifluoromethanesulfonate
Ethyl trifluoromethanesulfonate (CAS: 425-75-2; Formula: CF3SO2OC2H5) is a chemical compound with a molecular weight of 178.13 g/mol. It functions primarily as an effective ethylating agent in organic synthesis. This reagent is employed in various chemical transformations, particularly for the introduction of ethyl groups into different molecular structures, contributing to the synthesis of complex organic molecules.

Ethylating Agent
Ethyl trifluoromethanesulfonate is a potent reagent for ethylation reactions, readily transferring an ethyl group to nucleophiles. This is crucial in constructing carbon-carbon and carbon-heteroatom bonds during multi-step organic syntheses.
Organic Synthesis Intermediate
It serves as a versatile intermediate in the preparation of various organic compounds. Its reactivity allows for its use in reactions where milder ethylating agents may be insufficient.
Reagent for C-X Bond Formation
This compound is utilised in reactions that form carbon-heteroatom bonds, specifically non-halogenated C-X bonds. Its electrophilic nature makes it suitable for reactions with various nucleophilic substrates.
| Molecular weight | 178.13 |
|---|---|
| Linear formula | CF3SO2OC2H5 |
| Assay | 99% |
| Boiling point | 115 °C(lit.) |
| Density | 1.374 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.336(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 35 °C / 95 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl trifluoromethanesulfonate used for?
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Ethyl trifluoromethanesulfonate is primarily used as an ethylating agent in organic synthesis for the introduction of ethyl groups into various molecules, and in the formation of C-X bonds.
What are the CAS number and formula for Ethyl trifluoromethanesulfonate?
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The CAS number for Ethyl trifluoromethanesulfonate is 425-75-2, and its chemical formula is CF3SO2OC2H5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl trifluoromethanesulfonate with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should Ethyl trifluoromethanesulfonate be handled safely?
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Ethyl trifluoromethanesulfonate is a flammable liquid and vapour, and causes severe skin burns and eye damage. Handle with appropriate personal protective equipment including face shields, chemical-resistant gloves, and eye protection, in a well-ventilated area. Refer to the Safety Data Sheet for full handling instructions.
How is Ethyl trifluoromethanesulfonate shipped and exported?
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Ethyl trifluoromethanesulfonate is shipped and exported under UN 2920, Hazard Class 3 (Flammable Liquid) and 8 (Corrosive), Packing Group II. TSS ensures compliance with all relevant shipping regulations for international export.
How can I request a sample or quote for Ethyl trifluoromethanesulfonate?
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To request a sample or a quote for Ethyl trifluoromethanesulfonate, please contact our sales team through the website or by phone, providing your required quantity and shipping details.
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