Estren
Estren (CAS 35950-87-9), with the molecular formula C18H28O2 and a molecular weight of 276.41 g/mol, is a steroid hormone. It functions as a therapeutic alternative for maintaining bone mass in osteoporosis for both men and women. Research also indicates its potential to enhance neuronal viability through a pathway involving protein kinase C. It is supplied by TSS with an assay of ≥98.0% (TLC).
- IUPAC
- 4-Estren-3α,17β-diol

Osteoporosis Treatment
Estren serves as a therapeutic option to address bone mass reduction in osteoporosis, applicable to both female and male patients.
Neuronal Viability Enhancement
Studies suggest Estren can increase neuronal viability, comparable to estradiol, via a mechanism involving protein kinase C activation.
Hormone Replacement Therapy Alternative
It offers an alternative approach to hormone replacement therapy for conditions related to bone density maintenance.
| Molecular weight | 276.41 |
|---|---|
| Empirical formula | C18H28O2 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]/D +124±5°, c = 1 in methanol |
| Application | Therapeutic alternative to hormone replacement for osteoporosis of bone mass in both women and men.1,2 Estren increased neuronal viability to a similar extent as that observed with 17α- and 17β-estradiol, by a pathway mediated by protein kinase C.3 |
| Melting point | 203-207 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | USDEA Schedule III |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Estren used for?
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Estren (CAS 35950-87-9) is used as a therapeutic alternative for maintaining bone mass in osteoporosis in both men and women and has been shown to increase neuronal viability.
What is the CAS number and formula for Estren?
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The CAS number for Estren is 35950-87-9 and its molecular formula is C18H28O2.
What grade and purity does Tech Serve Solutions supply for Estren?
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Tech Serve Solutions supplies Estren with an assay of ≥98.0% determined by TLC. This is a research-grade chemical and is not represented as USP, BP, EP, or any other pharmacopoeia standard.
How should Estren be handled safely?
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Handling Estren requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, due to its classification with WGK Germany 3.
Is Estren a controlled substance?
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Yes, Estren is classified under USDEA Schedule III.
How is Estren packed and shipped by TSS?
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Tech Serve Solutions exports Estren globally. Specific packing and shipping details for your order can be provided upon request.
How can I request a quote or sample of Estren?
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To request a quote or sample of Estren, please contact our sales team directly through our website or by phone.
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