β-Estradiol 17-(β-D-glucuronide) sodium salt
β-Estradiol 17-(β-D-glucuronide) sodium salt (CAS: 15087-02-2) is a conjugate of the primary estrogen hormone, estradiol, with glucuronic acid. With the molecular formula C24H31O8Na and a molecular weight of 470.49, this compound is essential in biochemical research related to steroid hormone metabolism and signalling. It serves as a valuable tool for studying estrogenic effects in various biological systems, particularly in cell biology and endocrinology research.
- IUPAC
- 1,3,5(10)-Estratriene-3,17β-diol 17-glucuronide,3,17β-Dihydroxy-1,3,5(10)-estratriene 17-glucuronide
- Synonyms
- 1,3,5(10)-Estratriene-3,17β-diol 17-glucuronide, 3,17β-Dihydroxy-1,3,5(10)-estratriene 17-glucuronide
Endocrinology Research
This compound is utilized in studies investigating the physiological and pathological roles of estrogen and its metabolites. Researchers use it to explore hormone-receptor interactions and downstream signalling pathways.
Biochemical Assays
As a well-defined biochemical entity, it can be employed in assays to measure enzyme activity, particularly those involved in glucuronidation or deconjugation of steroid hormones. It also serves as a standard in analytical methods.
Cell Biology Studies
It is used in cell culture experiments to investigate the cellular responses to estrogenic compounds, including gene expression, cell proliferation, and differentiation. Its presence helps in understanding hormone-dependent cellular processes.
Drug Discovery and Development
The molecule may be used in preclinical research to evaluate potential therapeutic agents that modulate estrogen pathways or to understand the pharmacokinetics of estrogen conjugates.
| Molecular weight | 470.49 |
|---|---|
| Linear formula | C24H31O8Na |
| Storage temperature | −20°C |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
- H351Suspected of causing cancer
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-40 |
| Safety statements (S) | 22-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is β-Estradiol 17-(β-D-glucuronide) sodium salt used for?
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β-Estradiol 17-(β-D-glucuronide) sodium salt is primarily used in biochemical research, particularly in endocrinology, cell biology, and studies of steroid hormone metabolism and signalling. It serves as a standard in analytical methods and in assays investigating hormone-receptor interactions.
What are the CAS number and formula for β-Estradiol 17-(β-D-glucuronide) sodium salt?
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The CAS number is 15087-02-2 and the molecular formula is C24H31O8Na.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and laboratory use. Specific purity and assay details are available on the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should β-Estradiol 17-(β-D-glucuronide) sodium salt be handled safely?
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This compound is classified as harmful if swallowed, in contact with skin, or if inhaled, and is suspected of causing cancer. Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (type N100 or P3 filters), must be worn. Handle in a well-ventilated area.
Is β-Estradiol 17-(β-D-glucuronide) sodium salt a controlled substance?
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The provided data does not indicate that this specific compound is a controlled substance. However, users should always comply with local regulations regarding its possession and use.
How is this product packed and shipped?
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Tech Serve Solutions exports chemicals globally, adhering to all relevant shipping regulations for hazardous materials. Products are carefully packed to ensure stability and safety during transit. Please contact us for specific shipping and export inquiries.
How can I request a sample or quote?
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To request a sample or a quote for β-Estradiol 17-(β-D-glucuronide) sodium salt, please visit the product page on our website and use the 'Request a Quote' or 'Sample Request' function, or contact our sales team directly.
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