Dorzolamide
Dorzolamide (CAS: 120279-96-1), a potent carbonic anhydrase inhibitor with the molecular formula C10H16N2O4S3 and a molecular weight of 324.44 g/mol, is supplied by TSS for research applications. This compound is recognised for its role in cell biology and signaling pathways, particularly concerning nitric oxide and oxidative stress. Its specific stereochemistry is crucial for its biological activity. Available with an assay of ≥98% (HPLC).
- IUPAC
- (4S,6S)-4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide,4S,6S-Dorzolamide,L-671,152,MK-507
- Synonyms
- L-671,152MK-507(4S,6S)-4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide4S,6S-Dorzolamide

Carbonic Anhydrase Inhibition Research
Dorzolamide serves as a key reagent in studies investigating the function and inhibition of carbonic anhydrase enzymes. It is used to explore the physiological roles of these enzymes in various biological systems.
Cellular Signaling Pathway Investigations
This compound is valuable for researching cellular signaling mechanisms, particularly those involving nitric oxide and the cellular stress response. Its impact on oxidative stress pathways can be explored in controlled laboratory settings.
Neuroscience Research Tools
Dorzolamide finds application in neuroscience research, aiding the study of neural processes and the impact of enzyme inhibition on neuronal function. Its role in cell signaling within the nervous system is a focus area.
| Molecular weight | 324.44 |
|---|---|
| Empirical formula | C10H16N2O4S3 |
| Assay | ≥98% (HPLC) |
| Solubility | DMSO: soluble5 mg/mL (clear solution, warmed) |
| Optical activity | [α]/D -25 to -35°, c = 1 in methanol |
| Storage temperature | room temp |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dorzolamide used for?
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Dorzolamide is used for research in cell biology, cell signaling, neuroscience, cell stress, nitric oxide pathways, and oxidative stress. It acts as a carbonic anhydrase inhibitor.
What is the CAS number and formula for Dorzolamide?
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The CAS number for Dorzolamide is 120279-96-1, and its empirical formula is C10H16N2O4S3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dorzolamide with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Dorzolamide be handled and stored?
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Dorzolamide is classified as a Warning substance (GHS07) and may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area. Store at room temperature.
How is Dorzolamide packed and shipped?
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Dorzolamide is packed according to industry best practices for chemical reagents and is exported globally by Tech Serve Solutions. Please contact us for specific packaging and shipping details for your region.
How can I request a sample or quote for Dorzolamide?
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To request a sample or quote for Dorzolamide, please use the contact form on our website or reach out to our sales team directly.
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