Diethyl cyanophosphonate
Diethyl cyanophosphonate (CAS: 2942-58-7), with the linear formula (CH3CH2O)2P(O)CN and a molecular weight of 163.11 g/mol, is a valuable organophosphorus compound. It serves as a key building block and intermediate in organic synthesis. Diethyl cyanophosphonate is employed in the preparation of complex molecules, notably in the synthesis of analogs of epipodophyllotoxin, demonstrating its utility in pharmaceutical research and development.
- IUPAC
- DEPC,Diethyl phosphoryl cyanide
- Synonyms
- DEPCDiethyl phosphoryl cyanide
Organic Synthesis Intermediate
Diethyl cyanophosphonate functions as a versatile intermediate in the synthesis of complex organic molecules. Its reactivity allows for the introduction of specific functional groups, facilitating multi-step synthetic pathways.
Pharmaceutical Research
This compound has been utilised in the synthesis of 4-acylthiol-4-deoxy-4′-demethyl epipodophyllotoxin analogs. This application highlights its role in the development of potential therapeutic agents.
Building Block for Phosphorus Compounds
As a phosphonate derivative, Diethyl cyanophosphonate is a useful precursor for creating a variety of organophosphorus compounds with diverse applications.
| Molecular weight | 163.11 |
|---|---|
| Linear formula | (CH3CH2O)2P(O)CN |
| Assay | 90% |
| Boiling point | 104-105 °C/19 mmHg(lit.) |
| Density | 1.075 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.403(lit.) |
| Storage temperature | 2-8°C |
| Application | Diethyl cyanophosphonate was used in the synthesis of 4-acylthiol-4-deoxy-4′-demethyl epipodophyllotoxin analogs1. |
Hazard statements
- H300Fatal if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
- P302IF ON SKIN
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 80 °C / 176 °F |
| Transport (UN / ADR) | UN 2922 8/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+,C |
| Risk statements (R) | 26/27/28-32-34 |
| Safety statements (S) | 26-28-36/37-45 |
| Supplemental hazards | Contact with acids liberates very toxic gas. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diethyl cyanophosphonate used for?
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Diethyl cyanophosphonate is primarily used as a building block and intermediate in organic synthesis, particularly in pharmaceutical research for creating analogs of epipodophyllotoxin.
What is the CAS number and formula for Diethyl cyanophosphonate?
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The CAS number for Diethyl cyanophosphonate is 2942-58-7, and its linear formula is (CH3CH2O)2P(O)CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Diethyl cyanophosphonate with an assay of 90%. We do not represent this product as USP, BP, or EP grade.
How should Diethyl cyanophosphonate be handled safely?
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Diethyl cyanophosphonate is a highly toxic and corrosive substance. Handle with extreme care, using appropriate personal protective equipment including gloves, goggles, a faceshield, and a respirator. Contact with acids liberates very toxic gas. Store at 2-8°C.
How is Diethyl cyanophosphonate packed, shipped, and exported?
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Diethyl cyanophosphonate is securely packed according to international shipping regulations. Tech Serve Solutions is experienced in exporting fine chemicals globally.
How can I request a sample or quote for Diethyl cyanophosphonate?
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To request a sample or a quote for Diethyl cyanophosphonate, please contact our sales team through the website or by phone. We aim to respond promptly.
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