Diethyl (α-aminobenzyl)phosphonate hydrochloride
Diethyl (α-aminobenzyl)phosphonate hydrochloride (CAS 16656-50-1) is a chemical compound with the molecular formula C6H5CH(NH2)P(O)(OC2H5)2 · HCl and a molecular weight of 279.70 g/mol. Supplied by Tech Serve Solutions, this reagent is primarily utilised in organic synthesis. Its key applications include serving as a reactant in the synthesis of phosphonopeptides and in reactions involving phosphorous pentachloride, contributing to diverse C-C bond formation strategies.
- IUPAC
- (Aminophenylmethyl)phosphonic acid diethyl ester hydrochloride,NSC 113536

Phosphonopeptide Synthesis
Diethyl (α-aminobenzyl)phosphonate hydrochloride serves as a crucial building block in the synthesis of phosphonopeptides, which are analogues of naturally occurring peptides with modified properties.
Reaction with Phosphorus Pentachloride
This compound is employed as a reactant in reactions with phosphorous pentachloride, facilitating specific chemical transformations within synthetic pathways.
C-C Bond Formation
As a versatile reagent in organic chemistry, it contributes to the formation of carbon-carbon bonds, a fundamental process in the construction of complex organic molecules.
Chemical Synthesis Reagent
It is used as a synthetic reagent in various chemical synthesis processes, including those involving olefination and Horner-Wadsworth-Emmons reactions.
| Molecular weight | 279.70 |
|---|---|
| Linear formula | C6H5CH(NH2)P(O)(OC2H5)2 · HCl |
| Assay | 97% |
| Application | Reactant for: • Synthesis of phosphonopeptides1• reaction with phosphorous pentachloride2 |
| Melting point | 191 °C (dec.)(lit.) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diethyl (α-aminobenzyl)phosphonate hydrochloride used for?
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Diethyl (α-aminobenzyl)phosphonate hydrochloride is used as a reactant in organic synthesis, notably for the synthesis of phosphonopeptides and in reactions with phosphorous pentachloride. It is also applied in C-C bond formation, olefination, and as a general synthetic reagent.
What are the CAS number and molecular formula for Diethyl (α-aminobenzyl)phosphonate hydrochloride?
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The CAS number is 16656-50-1, and the molecular formula is C6H5CH(NH2)P(O)(OC2H5)2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Diethyl (α-aminobenzyl)phosphonate hydrochloride with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for this chemical?
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Diethyl (α-aminobenzyl)phosphonate hydrochloride is classified under WGK 2 in Germany, indicating it is hazardous to water. It has a melting point of 191 °C (dec.). Appropriate safety precautions should be taken during handling.
How is Diethyl (α-aminobenzyl)phosphonate hydrochloride packed and shipped?
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Tech Serve Solutions reliably packs and exports fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to all necessary regulations for safe and compliant shipment.
How can I request a sample or quote for Diethyl (α-aminobenzyl)phosphonate hydrochloride?
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To request a sample or a quotation, please contact our sales team directly through the website or by phone, providing the product name and CAS number.
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