Devazepide

CAS 103420-77-5C25H20N4O2Cell Biology

Devazepide (CAS: 103420-77-5), with the molecular formula C25H20N4O2 and a molecular weight of 408.45 g/mol, is a potent and selective cholecystokinin (CCK) receptor antagonist. This white to off-white powder is primarily utilised in scientific research for its ability to block CCK-A and CCK-B receptors. Its applications are mainly within neurochemical and pharmacological investigations, particularly concerning their role in gastrointestinal functions and central nervous system processes.

IUPAC: (S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)indole-2-carboxamide,L-364,718,MK 329
Synonyms: (S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)indole-2-carboxamideL-364,718MK 329

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Devazepide (C25H20N4O2) — chemical structure, CAS 103420-77-5; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesCell BiologyD-DIFMerck More...

01 /Applications

Pharmacological Research Tool

Devazepide serves as a critical tool for researchers investigating the physiological roles of cholecystokinin (CCK) receptors in both the central and peripheral nervous systems. Its high selectivity allows for precise studies into CCK-mediated effects.

Neuroscience and Behavioral Studies

As a CCK receptor antagonist, Devazepide is employed in neuroscience to explore CCK's influence on appetite, satiety, anxiety, and pain perception. This aids in understanding potential therapeutic targets for neurological and psychiatric disorders.

Gastrointestinal Physiology Research

The compound is used to study the role of CCK receptors in regulating gastric emptying, pancreatic secretion, and gall bladder contraction. This research contributes to a deeper understanding of digestive system regulation.

02 /Properties

Molecular weight	408.45
Empirical formula	C25H20N4O2
Assay	≥98% (HPLC)
Form	powder
Colour	white to off-white
Solubility	DMSO: >5 mg/mL
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash thoroughly after handling
P301IF SWALLOWED

Transport (UN / ADR)	UN 2811 6.1 / PGI
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T+
Risk statements (R)	28
Safety statements (S)	28-36/37-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

103420-77-5

05 /Additional specifications

Storage Condition	desiccated

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Devazepide used for?

Devazepide (CAS: 103420-77-5) is used as a selective cholecystokinin (CCK) receptor antagonist primarily in scientific research, particularly in neuroscience, behavioural studies, and gastrointestinal physiology research.

What are the CAS number and formula for Devazepide?

The CAS number for Devazepide is 103420-77-5 and its molecular formula is C25H20N4O2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Devazepide with an assay of ≥98% (HPLC). This product is intended for research purposes and is not supplied as USP, BP, EP, or any other pharmacopoeia grade.

How should Devazepide be handled safely?

Devazepide is classified as toxic if swallowed (H300) and carries a 'Danger' signal word. Handle with extreme caution in a well-ventilated area, wearing appropriate personal protective equipment, and avoid any ingestion. Refer to the Safety Data Sheet for full handling instructions.

How is Devazepide packed and shipped?

Devazepide is supplied as a white to off-white powder and should be stored at 2-8°C in a desiccated state. We adhere to all regulations for the safe packing, handling, and export of chemical compounds.