D-(+)-Gluconic acid δ-lactone
D-(+)-Gluconic acid δ-lactone (CAS: 90-80-2, C6H10O6) is a cyclic ester of D-gluconic acid and a valuable intermediate in carbohydrate chemistry. Possessing a molecular weight of 178.14 g/mol, this compound is widely employed in chemical synthesis and as a key component in various industrial applications. Its controlled hydrolysis in aqueous solutions yields gluconic acid, making it a useful acidulant and sequestrant in diverse formulations.
- IUPAC
- δ-Gluconolactone,1,2,3,4,5-Pentahydroxycaproic acid δ-lactone,D-(+)-Dextronic acid δ-lactone
- Synonyms
- D-Glucono-1,5-lactoneGlucono delta-lactoneD-(+)-Dextronic acid delta-lactoneδ-Gluconolactone

Chemical Synthesis
D-(+)-Gluconic acid δ-lactone serves as a versatile building block in organic synthesis, particularly for the preparation of carbohydrate derivatives and other complex organic molecules. Its lactone form offers unique reactivity compared to its parent acid.
Acidulant and Sequestrant
Upon dissolution in water, it slowly hydrolyses to gluconic acid, providing a mild and controlled acidification. This property is valuable in food applications (where permitted) and in industrial processes requiring gradual pH adjustment or metal ion chelation.
Biotechnology and Research
The compound is utilised in biochemical research and biotechnological processes, contributing to studies involving carbohydrate metabolism and enzyme activity. Its role in controlled acid release is of particular interest.
| Molecular weight | 178.14 |
|---|---|
| Empirical formula | C6H10O6 |
| Assay | ≥99.0% (T) |
| Grade | purum |
| Optical activity | [α]20/D +66.0±1°, c = 4% in H2O |
| Melting point | 154-162 °C160 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-(+)-Gluconic acid δ-lactone used for?
+
D-(+)-Gluconic acid δ-lactone is used in chemical synthesis, as a controlled acidulant and sequestrant, and in biotechnology and research applications.
What is the CAS number and molecular formula for D-(+)-Gluconic acid δ-lactone?
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The CAS number is 90-80-2 and the molecular formula is C6H10O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies D-(+)-Gluconic acid δ-lactone in purum grade with an assay of ≥99.0% (T). We do not represent this product as USP, BP, or EP grade.
How should D-(+)-Gluconic acid δ-lactone be handled?
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Handle with care, using appropriate personal protective equipment including eyeshields and gloves. Ensure adequate ventilation and use a suitable respirator filter (type N95 or P1) if dust is generated. This compound has a WGK Germany rating of 3.
Is D-(+)-Gluconic acid δ-lactone a controlled substance?
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Based on the provided data, there is no indication that D-(+)-Gluconic acid δ-lactone is a controlled substance.
How is D-(+)-Gluconic acid δ-lactone typically shipped and exported?
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Tech Serve Solutions, a global supplier, exports fine chemicals and reagents worldwide, adhering to all necessary regulations for safe and compliant international shipment.
How can I request a sample or quote for D-(+)-Gluconic acid δ-lactone?
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Please contact our sales team through the website or by phone to request a sample or a detailed quotation for your specific requirements.
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