Cytochalasin A from Drechslera dematioidea
Cytochalasin A (CAS: 14110-64-6), a potent inhibitor of actin polymerisation, is a bioactive small molecule derived from the mold *Drechslera dematioidea*. With the molecular formula C29H35NO5 and a molecular weight of 477.59 g/mol, this compound is extensively utilised in cell biology research for studying cytoskeletal dynamics and cell signalling pathways. Its specific mechanism of action makes it a valuable tool for investigating cellular processes affected by actin disruption.
Actin Polymerisation Inhibition
Cytochalasin A selectively inhibits the polymerisation of actin filaments, providing a critical tool for researchers studying the dynamics of the cytoskeleton and its role in cellular functions like motility, cell division, and shape maintenance.
Cell Biology Research
As a key bioactive small molecule, it is applied in various cell biology studies to probe cellular mechanisms, including cell signalling, intracellular transport, and cell cycle progression, by observing the effects of actin disruption.
Cytoskeletal Dynamics Studies
This compound is instrumental in exploring the complex interplay within the cytoskeleton and extracellular matrix, helping to elucidate how cellular structure influences cellular behaviour and response to stimuli.
Neuroscience and Cell Signaling Research
Cytochalasin A is employed in research focused on cell signaling pathways and neuroscience to understand the role of the actin cytoskeleton in neuronal development, function, and synaptic plasticity.
| Molecular weight | 477.59 |
|---|---|
| Empirical formula | C29H35NO5 |
| Storage temperature | −20°C |
Hazard statements
- H300Fatal if swallowed
- H310Fatal in contact with skin
- H330Fatal if inhaled
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P302IF ON SKIN
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 1544 6.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 63-26/27/28 |
| Safety statements (S) | 28-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cytochalasin A used for?
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Cytochalasin A is primarily used as a research tool to inhibit actin polymerisation, aiding studies in cell biology, cytoskeletal dynamics, cell signalling, and neuroscience.
What are the CAS number and formula for Cytochalasin A?
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The CAS number for Cytochalasin A is 14110-64-6, and its empirical formula is C29H35NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Cytochalasin A as a research-grade chemical. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should Cytochalasin A be handled safely?
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Cytochalasin A is a highly toxic substance requiring strict safety precautions. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a full-face particle respirator (N100 US/P3 EN143). Avoid inhalation, ingestion, and skin contact. Refer to the Safety Data Sheet for detailed handling procedures.
Is Cytochalasin A a controlled substance?
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The provided data does not indicate that Cytochalasin A is a controlled substance. However, users should consult local regulations.
How is Cytochalasin A packed, shipped, and exported?
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Cytochalasin A is packed, shipped, and exported in accordance with relevant regulations for hazardous materials, typically stored at -20°C.
How can I request a quote or sample for Cytochalasin A?
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To request a quote or sample, please contact our sales team through the website or by phone, providing your contact details and requirements.
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