Chlorodimethylethylsilane
Chlorodimethylethylsilane (CAS: 6917-76-6), with the formula C2H5Si(CH3)2Cl and a molecular weight of 122.67 g/mol, is a silicon-based chemical reagent. It is primarily utilized in organic synthesis, particularly for the protection and derivatization of various functional groups. Its specific chemical structure makes it valuable in introducing the dimethylethylsilyl group during complex synthetic pathways.
- IUPAC
- Chloro(ethyl)dimethylsilane,Dimethylethylchlorosilane
- Synonyms
- Chloro(ethyl)dimethylsilaneDimethylethylchlorosilane

Protecting Group Reagent
Chlorodimethylethylsilane serves as a reagent for introducing the dimethylethylsilyl (EtSiMe2-) protecting group onto hydroxyl or other nucleophilic functionalities in organic synthesis. This temporary modification facilitates selective reactions elsewhere in the molecule.
Derivatization for Analysis
It can be employed in derivatization strategies to enhance the volatility or detectability of analytes, particularly in chromatographic techniques. This aids in the analysis of complex organic compounds.
Intermediate in Silicon Chemistry
As a chlorosilane, it acts as a versatile building block in the synthesis of more complex organosilicon compounds and polymers, leveraging the reactivity of the silicon-chlorine bond.
| Molecular weight | 122.67 |
|---|---|
| Linear formula | C2H5Si(CH3)2Cl |
| Assay | 97% |
| Boiling point | 89.2 °C(lit.) |
| Density | 0.873 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.406(lit.) |


Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -8 °C / 17.6 °F |
| Transport (UN / ADR) | UN 2985 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-34 |
| Safety statements (S) | 16-26-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chlorodimethylethylsilane used for?
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Chlorodimethylethylsilane is used in chemical synthesis, primarily as a protecting group reagent to derivatize functional groups like hydroxyls, and as an intermediate in the creation of more complex organosilicon compounds.
What are the CAS number and formula for Chlorodimethylethylsilane?
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The CAS number is 6917-76-6, and the chemical formula is C2H5Si(CH3)2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chlorodimethylethylsilane at a minimum purity of 97% (assay). This product is supplied for research and laboratory use; TSS does not represent it as USP, BP, or EP grade.
What are the main hazards associated with Chlorodimethylethylsilane?
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Chlorodimethylethylsilane is a highly flammable liquid and vapour (H225) and causes severe skin burns and eye damage (H314). It requires careful handling in a well-ventilated area, away from ignition sources, and with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection.
How is Chlorodimethylethylsilane packed and shipped?
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This product is shipped under UN 2985, Hazard Class 8 (corrosive) with subsidiary risk 3 (flammable), Packing Group II. Packaging adheres to stringent international regulations for the safe transport of hazardous chemicals.
How can I request a sample or quote for Chlorodimethylethylsilane?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team via our website or by phone, providing your contact details and the required quantity.
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