CBIO
6-Chloro-1,2-benzisoxazol-3(2H)-one (CAS: 61977-29-5) is a chemical compound with the molecular formula C7H4ClNO2 and a molecular weight of 169.57 g/mol. It is primarily utilised in research settings, particularly within cell biology and neuroscience. Its specific applications often relate to the modulation of ion channels and ligand-gated ion channels, making it a valuable tool for studying cellular signalling pathways. Supplied by Tech Serve Solutions, this compound is available for various laboratory investigations.
- IUPAC
- 6-Chloro-1,2-benzisoxazol-3(2H)-one,6-Chloro-3-hydroxy-1,2-benzisoxazole,6-Chloro-3-hydroxybenzisoxazole,6-Chlorobenzo[d]isoxazol-3-ol
- Synonyms
- 6-Chloro-1,2-benzisoxazol-3(2H)-one6-Chloro-3-hydroxy-1,2-benzisoxazole6-Chloro-3-hydroxybenzisoxazole6-Chlorobenzo[d]isoxazol-3-ol

Ion Channel Research
This compound serves as a modulator for various ion channels, including ligand-gated ion channels. It is instrumental in electrophysiology studies and understanding ion transport mechanisms within cells.
Cellular Signalling Studies
Utilised in neuroscience and cell biology, it aids in investigating complex cellular signalling pathways. Its effects on ionotropic glutamate receptors are of particular research interest.
Pharmacological Tool
As a research chemical, it can be employed in the development and validation of assays for drug discovery, specifically targeting neurological pathways and receptor function.
| Molecular weight | 169.57 |
|---|---|
| Empirical formula | C7H4ClNO2 |
| Assay | ≥95% (HPLC) |
| Solubility | DMSO: soluble15 mg/mL (clear solution) |
| Storage temperature | room temp |

Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Chloro-1,2-benzisoxazol-3(2H)-one used for?
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This compound is primarily used in research settings for studying cell biology, cell signalling, neuroscience, and ion channels, particularly ionotropic glutamate receptor modulators.
What are the CAS number and molecular formula?
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The CAS number for 6-Chloro-1,2-benzisoxazol-3(2H)-one is 61977-29-5, and its molecular formula is C7H4ClNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6-Chloro-1,2-benzisoxazol-3(2H)-one with an assay of ≥95% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 6-Chloro-1,2-benzisoxazol-3(2H)-one be handled?
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This compound has a GHS07 symbol and a Warning signal word, with hazard statement H302 (Harmful if swallowed). Handle with appropriate personal protective equipment in a well-ventilated area.
How is this chemical stored and shipped?
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This chemical is typically stored at room temperature and is available for export globally by Tech Serve Solutions.
How can I request a quote or sample?
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Please contact our sales team through the website or by phone to request a quote or sample of 6-Chloro-1,2-benzisoxazol-3(2H)-one.
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