Carmofur

CAS 61422-45-5C11H16FN3O3Cell Biology

Carmofur (CAS: 61422-45-5), with the molecular formula C11H16FN3O3 and a molecular weight of 257.26 g/mol, is a fluorinated pyrimidine derivative. It functions as a DNA synthesis inhibitor, impacting DNA metabolism and transcription. Carmofur is primarily utilised in biochemical research for studies related to apoptosis, cell cycle regulation, and gene expression.

IUPAC: 1-Hexylcarbamoyl-5-fluorouracil,HCFU

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Carmofur (C11H16FN3O3) — chemical structure, CAS 61422-45-5; Life Science, fine chemical supplied by Tech Serve Solutions

Apoptosis and Cell CycleCell BiologyDNA Synthesis InhibitorsDNA metabolism

01 /Applications

DNA Synthesis Inhibition

Carmofur acts by inhibiting thymidylate synthase, a key enzyme in DNA synthesis. This mechanism makes it a valuable tool for researchers studying DNA replication and repair processes.

Apoptosis and Cell Cycle Research

As an inhibitor of DNA synthesis, Carmofur can induce programmed cell death (apoptosis) and disrupt the cell cycle. It is employed in cellular biology to investigate these fundamental processes.

Gene Regulation Studies

By affecting DNA metabolism, Carmofur can influence gene expression patterns. Researchers use it to explore the regulation of genes involved in various cellular functions.

02 /Properties

Molecular weight	257.26
Empirical formula	C11H16FN3O3
Assay	≥98% (HPLC)
Form	powder
Colour	white to off-white
Solubility	DMSO: >15 mg/mL
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Danger

Hazard statements

H301Toxic if swallowed
H361Suspected of damaging fertility or the unborn child

Precautionary statements

P281Use personal protective equipment as required
P301IF SWALLOWED

Transport (UN / ADR)	UN 2811 6.1 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	60-61-25
Safety statements (S)	45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

61422-45-5

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Carmofur primarily used for?

Carmofur is primarily used in research for its role as a DNA synthesis inhibitor, impacting apoptosis, cell cycle regulation, and gene expression studies.

What is the CAS number and chemical formula for Carmofur?

The CAS number for Carmofur is 61422-45-5, and its chemical formula is C11H16FN3O3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Carmofur with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.

How should Carmofur be handled and stored?

Carmofur is a Danger substance, harmful if swallowed and suspected of damaging fertility or the unborn child. It should be handled with appropriate personal protective equipment in a well-ventilated area and stored at 2-8°C.