Butyryl chloride
Butyryl chloride (CAS: 141-75-3), with the linear formula CH3CH2CH2COCl and a molecular weight of 106.55 g/mol, is a reactive acyl halide. It is commonly employed as a chemical intermediate and building block in organic synthesis. Butyryl chloride is utilized in esterification reactions and for the introduction of the butyryl group into various organic molecules, contributing to the synthesis of more complex compounds.

Esterification Agent
Butyryl chloride serves as an effective agent for esterification. It has been documented for its use in esterifying wood meal dissolved in ionic liquids, facilitating the modification of biomass.
Organic Synthesis Building Block
As a reactive acyl halide, butyryl chloride is a valuable building block in organic chemistry. It is used to introduce the butyryl moiety into diverse organic structures, enabling the synthesis of pharmaceuticals and other fine chemicals.
Intermediate in Chemical Synthesis
This compound functions as a key intermediate in various chemical synthesis pathways. Its reactivity allows for diverse derivatisation, making it useful in the production of specialised organic molecules.
| Molecular weight | 106.55 |
|---|---|
| Linear formula | CH3CH2CH2COCl |
| Assay | 98% |
| Boiling point | 102 °C(lit.) |
| Density | 1.026 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.412(lit.) |
| Vapour density | 3.7 (vs air) |
| Melting point | −89 °C(lit.) |
| Application | Butyryl chloride has been used to esterify wood meal dissolved in the ionic liquid, 1-butyl-3-methylimidazolium chloride1. |



Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H331Toxic if inhaled
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 18 °C / 64.4 °F |
| Transport (UN / ADR) | UN 2353 8(3) / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-34 |
| Safety statements (S) | 16-23-26-36-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Butyryl chloride used for?
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Butyryl chloride is used as a chemical intermediate and building block in organic synthesis, notably for esterification reactions and introducing the butyryl group into organic molecules.
What is the CAS number and formula for Butyryl chloride?
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The CAS number for Butyryl chloride is 141-75-3, and its linear formula is CH3CH2CH2COCl.
What grade and purity does Tech Serve Solutions supply for Butyryl chloride?
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Tech Serve Solutions supplies Butyryl chloride with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should Butyryl chloride be handled safely?
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Butyryl chloride is a highly flammable liquid and vapour (H225) and causes severe skin burns and eye damage (H314), and is toxic if inhaled (H331). Handle with extreme caution in a well-ventilated area, using appropriate personal protective equipment including gloves, goggles, a face shield, and a suitable respirator. Store away from ignition sources.
Is Butyryl chloride packed and shipped internationally?
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Yes, Tech Serve Solutions exports and supplies Butyryl chloride globally. It is shipped according to relevant dangerous goods regulations, identified as UN 2353, Hazard Class 8(3), Packing Group II.
How can I request a sample or quote for Butyryl chloride?
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To request a sample or a quote for Butyryl chloride, please contact our sales team through the website or by phone. Please specify the quantity required and your delivery location.
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