Bis(trimethylsilyl) phosphite
Bis(trimethylsilyl) phosphite (CAS: 3663-52-3), with the molecular formula C6H19O3PSi2 and a molecular weight of 226.36 g/mol, is a valuable organophosphorus compound. It functions as a versatile building block in organic synthesis and is primarily utilised in chemical research and development. Its specific chemical properties make it suitable for various synthetic transformations, contributing to the creation of more complex molecules in diverse chemical applications.

Organic Synthesis Reagent
Bis(trimethylsilyl) phosphite serves as a key reagent in various organic transformations. It is employed in the synthesis of organophosphorus compounds and can act as a silylating agent in specific reaction pathways.
Phosphorus Chemistry
This compound is a significant phosphorus source in research laboratories undertaking studies in phosphorus chemistry. Its structure allows for its incorporation into novel phosphorus-containing molecules.
Building Block for Complex Molecules
As an organic building block, Bis(trimethylsilyl) phosphite is utilized in multi-step syntheses to construct complex molecular architectures for advanced chemical research.
| Molecular weight | 226.36 |
|---|---|
| Empirical formula | C6H19O3PSi2 |
| Assay | ≥98.0% (GC) |
| Boiling point | 77-79 °C/11 mmHg |
| Density | 0.968 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.412 |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 58 °C / 136.4 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bis(trimethylsilyl) phosphite used for?
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Bis(trimethylsilyl) phosphite is primarily used as a reagent and building block in organic synthesis, particularly in the field of phosphorus chemistry and for constructing complex molecules.
What are the CAS number and chemical formula for Bis(trimethylsilyl) phosphite?
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The CAS number for Bis(trimethylsilyl) phosphite is 3663-52-3, and its empirical formula is C6H19O3PSi2.
What grade and purity does Tech Serve Solutions supply for Bis(trimethylsilyl) phosphite?
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Tech Serve Solutions supplies Bis(trimethylsilyl) phosphite with a purity of ≥98.0% (GC). This product is supplied for research and development purposes and is not represented as USP, BP, or EP grade.
What are the key safety considerations when handling Bis(trimethylsilyl) phosphite?
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Bis(trimethylsilyl) phosphite is a flammable liquid and vapour (H226) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, should be used. Handle in a well-ventilated area.
How is Bis(trimethylsilyl) phosphite typically packed and shipped?
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Bis(trimethylsilyl) phosphite is packed according to international shipping regulations for hazardous materials, including UN 1993 classification. TSS exports globally, adhering to all necessary compliance standards.
How can I request a sample or quote for Bis(trimethylsilyl) phosphite?
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To request a sample or a quote for Bis(trimethylsilyl) phosphite, please contact our sales team through the website or by phone, providing your specific requirements.
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