Azelnidipine

CAS 123524-52-7C33H34N4O6Cell Biology

Azelnidipine (CAS: 123524-52-7) is a dihydropyridine derivative with the molecular formula C33H34N4O6 and a molecular weight of 582.65 g/mol. As a potent L-type calcium channel blocker, it functions as an antihypertensive agent. Its applications extend to preventing cardiac dysfunction post-stress and potentially mitigating inflammation associated with atherosclerosis. Azelnidipine is supplied as a powder.

IUPAC: 2-Amino-1,4-dihydro-6-methyl-4-(3 nitrophenyl)-3,5-pyridinedicarboxylic acid 3-[1-(diphenylmethyl)-3-azetidinyl] 5-(1-methylethyl) ester,CS-905,RS-9054
Synonyms: 2-Amino-1,4-dihydro-6-methyl-4-(3 nitrophenyl)-3,5-pyridinedicarboxylic acid 3-[1-(diphenylmethyl)-3-azetidinyl] 5-(1-methylethyl) esterCS-905RS-9054

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Azelnidipine (C33H34N4O6) — chemical structure, CAS 123524-52-7; Life Science, fine chemical supplied by Tech Serve Solutions

AN-AZBioactive Small MoleculesCalcium Channel ModulatorsCell BiologyDaiichi-SankyoInhibitors and ActivatorsIon Channels

01 /Applications

Antihypertensive Agent

Azelnidipine functions as an L-type calcium channel blocker, making it effective in managing hypertension. Its acute administration has demonstrated a protective role in cardiac function following stress.

Cardioprotection and Atherosclerosis Research

Research indicates that Azelnidipine may offer a protective effect against inflammation linked to atherosclerosis. It is also studied for its ability to preserve cardiac function after acute stress.

Calcium Channel Modulation

As a calcium channel modulator, Azelnidipine plays a role in cellular signaling pathways, particularly those involving voltage-gated ion channels, impacting cell biology and neuroscience research.

02 /Properties

Molecular weight	582.65
Empirical formula	C33H34N4O6
Assay	≥98% (HPLC)
Form	powder
Solubility	DMSO: >10 mg/mL
Storage temperature	room temp
Application	Azelnidipine is a novel dihydropyridine derivative, a L-type calcium channel blocker, and an antihypertensive. Acute administration of azelnidipine prevents a sudden drop of cardiac function after acute stress. Azelnidipine may have a protective role in inflammation associated with atherosclerosis.

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Danger

Hazard statements

H302Harmful if swallowed
H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22-41
Safety statements (S)	26-39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

123524-52-7

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Azelnidipine used for?

Azelnidipine is used as an antihypertensive agent due to its action as an L-type calcium channel blocker. It is also investigated for cardioprotective effects and potential roles in managing inflammation associated with atherosclerosis.

What is the CAS number and molecular formula for Azelnidipine?

The CAS number for Azelnidipine is 123524-52-7, and its molecular formula is C33H34N4O6.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Azelnidipine with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.

How should Azelnidipine be handled safely?

Azelnidipine is classified as Danger with hazards including H302 (Harmful if swallowed) and H318 (Causes serious eye damage). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Avoid dust formation and ensure adequate ventilation.

How is Azelnidipine packaged, shipped, and exported?

Azelnidipine is typically supplied as a powder and stored at room temperature. Tech Serve Solutions, as a global supplier and exporter, can provide details on packaging and international shipping upon request.