6α-Methylprednisolone 21-hemisuccinate sodium salt
6α-Methylprednisolone 21-hemisuccinate sodium salt (CAS: 2375-03-3; Formula: C26H33O8Na; MW: 496.53) is a biologically active small molecule, an ester derivative of a synthetic corticosteroid. It functions as a glucocorticoid and is utilized in research settings for its anti-inflammatory and immunosuppressive properties, primarily in cell biology and cell signaling studies. Supplied by Tech Serve Solutions.
- IUPAC
- 6α-Methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-hemisuccinate

Cell Biology Research
Investigate cellular responses to corticosteroid signaling pathways. This compound can be used to study gene expression modulation and inflammatory processes within cell cultures.
Cell Signaling Studies
Explore the intricate mechanisms of cellular communication. 6α-Methylprednisolone 21-hemisuccinate sodium salt aids in understanding the role of glucocorticoid receptors in signal transduction.
Neuroscience Research
Examine the impact of corticosteroids on neuronal function and neuroinflammation. This compound can be a tool for studying neurological disease models and glia-astrocyte interactions.
Hormone Research
Used as a synthetic steroid hormone analogue in biochemical and physiological studies. It can help elucidate the broader endocrine system's regulatory mechanisms.
| Molecular weight | 496.53 |
|---|---|
| Linear formula | C26H33O8Na |
| Form | lyophilized powder |

Hazard statements
- H351Suspected of causing cancer
- H360May damage fertility or the unborn child
Precautionary statements
- P201Obtain special instructions before use
- P281Use personal protective equipment as required
- P308IF exposed or concerned
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 61-40 |
| Safety statements (S) | 53-22-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6α-Methylprednisolone 21-hemisuccinate sodium salt used for?
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In research settings, it is used in cell biology, cell signaling, neuroscience, and hormone studies due to its corticosteroid properties, particularly for investigating anti-inflammatory and immunosuppressive mechanisms.
What are the CAS number and molecular formula?
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The CAS number is 2375-03-3, and the molecular formula is C26H33O8Na.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a lyophilized powder. We provide technical and research grades, and do not represent it as USP, BP, or EP grade unless explicitly stated in specific product documentation.
What are the safety considerations for handling this compound?
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This compound is classified as 'Danger' (GHS08) and carries hazard statements H351 (suspected of causing cancer) and H360 (may damage fertility or the unborn child). Appropriate PPE including eyeshields, gloves, and a suitable respirator (e.g., N100 or P3) must be used. Handle with extreme caution in a well-ventilated area or fume hood.
Is this compound a controlled substance?
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The provided data does not indicate this compound is a controlled substance. However, users should consult local regulations.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals. Packaging and shipping methods adhere to international regulations for chemical transport. Specific details can be provided upon request.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales department via the website or direct email, providing the product name and CAS number.
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