6-Chloro-3-pyridinecarbonitrile
6-Chloro-3-pyridinecarbonitrile (CAS: 33252-28-7), with the molecular formula C6H3ClN2 and a molecular weight of 138.55 g/mol, is a halogenated heterocyclic building block. This compound is valuable in organic synthesis, particularly for the construction of more complex pyridine derivatives. Its reactivity makes it a useful intermediate in the chemical industry for various synthetic pathways.
- IUPAC
- 2-Chloro-5-cyanopyridine,2-Chloropyridine-5-carbonitrile
- Synonyms
- 2-Chloro-5-cyanopyridine2-Chloropyridine-5-carbonitrile

Organic Synthesis Intermediate
6-Chloro-3-pyridinecarbonitrile serves as a key intermediate in the synthesis of diverse organic molecules. Its structure allows for various substitution and coupling reactions, enabling the creation of novel compounds.
Pharmaceutical Research
This compound is utilised in the development of new pharmaceutical agents. Its pyridine core and nitrile functionality are common features in biologically active molecules.
Agrochemical Development
The compound can be employed in the synthesis of agrochemicals, contributing to the creation of new crop protection agents and pesticides.
Material Science
It may find application in the synthesis of functional materials due to its unique structural characteristics, influencing material properties.
| Molecular weight | 138.55 |
|---|---|
| Empirical formula | C6H3ClN2 |
| Assay | 97% |
| Melting point | 116-120 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Chloro-3-pyridinecarbonitrile used for?
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6-Chloro-3-pyridinecarbonitrile is primarily used as a building block and intermediate in organic synthesis, particularly for pharmaceuticals, agrochemicals, and material science applications.
What are the CAS number and formula for 6-Chloro-3-pyridinecarbonitrile?
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The CAS number for 6-Chloro-3-pyridinecarbonitrile is 33252-28-7, and its molecular formula is C6H3ClN2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6-Chloro-3-pyridinecarbonitrile with an assay of 97%. This product is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 6-Chloro-3-pyridinecarbonitrile be handled?
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Handle 6-Chloro-3-pyridinecarbonitrile with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure good ventilation and avoid inhalation of dust, ingestion, and contact with skin and eyes, as it is harmful if swallowed, in contact with skin, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation.
Is 6-Chloro-3-pyridinecarbonitrile a controlled substance?
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Based on the provided data, there is no indication that 6-Chloro-3-pyridinecarbonitrile is a controlled substance.
How is 6-Chloro-3-pyridinecarbonitrile packed and shipped?
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6-Chloro-3-pyridinecarbonitrile is packed to ensure safe transit. Tech Serve Solutions is experienced in exporting chemicals globally, adhering to all relevant shipping regulations.
How can I request a quote or sample for 6-Chloro-3-pyridinecarbonitrile?
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To request a quote or sample, please contact the Tech Serve Solutions sales team via the website or provide your specific requirements through the enquiry form.
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