5-Fluoro-2-hydroxypyridine
5-Fluoro-2-hydroxypyridine (CAS: 51173-05-8), with the molecular formula C5H4FNO and a molecular weight of 113.09 g/mol, is a versatile fluorinated heterocyclic building block. It serves as a key intermediate in the synthesis of various organic compounds. Its structure makes it valuable in research and development, particularly within the pharmaceutical and agrochemical sectors, for constructing complex molecules requiring a fluoropyridine moiety.
- IUPAC
- 5-Fluoro-2-pyridinol
- Synonyms
- 5-Fluoro-2-pyridinol

Pharmaceutical Synthesis
Used as a crucial intermediate in the development of novel pharmaceutical agents. Its fluoropyridine structure can be incorporated into drug candidates to modulate pharmacological properties like metabolic stability and binding affinity.
Agrochemical Research
Serves as a building block for synthesizing new agrochemicals, including herbicides, insecticides, and fungicides. The incorporation of fluorine can enhance the efficacy and selectivity of these crop protection agents.
Material Science
Explored as a component in the design of advanced materials. Its unique electronic and structural properties can be leveraged in the development of functional organic materials.
Organic Synthesis Intermediate
A valuable reagent in general organic synthesis for introducing the 5-fluoro-2-pyridyl group into various molecular architectures. It facilitates access to a range of substituted pyridine derivatives.
| Molecular weight | 113.09 |
|---|---|
| Empirical formula | C5H4FNO |
| Assay | 97% |
| Melting point | 150-155 °C |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Fluoro-2-hydroxypyridine used for?
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5-Fluoro-2-hydroxypyridine is primarily used as a versatile building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals, and in material science research.
What is the CAS number and molecular formula for 5-Fluoro-2-hydroxypyridine?
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The CAS number is 51173-05-8 and the molecular formula is C5H4FNO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Fluoro-2-hydroxypyridine with an assay of 97%. We do not represent this product as USP, BP, EP or other pharmacopoeia grades.
How should 5-Fluoro-2-hydroxypyridine be handled safely?
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This compound is classified as Danger. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection in a well-ventilated area. Avoid dust formation and inhalation.
Is 5-Fluoro-2-hydroxypyridine a controlled substance?
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Based on the provided data, there is no indication that 5-Fluoro-2-hydroxypyridine is a controlled substance.
How is 5-Fluoro-2-hydroxypyridine packed and shipped?
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Tech Serve Solutions packages and exports chemicals according to international shipping regulations, ensuring safe and compliant transit.
How can I request a quote or sample for 5-Fluoro-2-hydroxypyridine?
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To request a quote or sample, please contact our sales team through the website or by phone, providing the product name and CAS number (51173-05-8).
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