5,5-Diphenyl-2-thiohydantoin
5,5-Diphenyl-2-thiohydantoin (CAS: 21083-47-6) is a heterocyclic organic compound with a molecular weight of 268.33 g/mol. This thiohydantoin derivative serves as a valuable building block and reactant in organic synthesis. Its applications span the creation of diverse imidazole and imidazothiazole derivatives, finding utility in the development of antimicrobial agents, anti-cancer compounds, and inhibitors for enzymes such as fatty acid amide hydrolase and acyl CoA: cholesterol acyltransferase.
- IUPAC
- 5,5-Diphenyl-2-thioxo-4-imidazolidinone,5,5-Diphenylimidazolidine-4-one-2-thione,DPTH
- Synonyms
- C15H12N2OS5,5-Diphenylimidazolidine-4-one-2-thione5,5-Diphenyl-2-thioxo-4-imidazolidinoneDPTH
Synthesis of Imidazole Derivatives
5,5-Diphenyl-2-thiohydantoin is a key reactant for the synthesis of various imidazole derivatives, contributing to the exploration of novel heterocyclic compounds.
Development of Antimicrobial Agents
This compound is utilised in the preparation of imidazothiazole and glycocyamidine derivatives, which are investigated for their potential antimicrobial properties.
Enzyme Inhibitor Research
It serves as a template for the development of inhibitors targeting enzymes such as fatty acid amide hydrolase (FAAH) and acyl CoA: cholesterol acyltransferase (ACAT), relevant in various biological pathways.
Precursor for Anti-cancer Agents
5,5-Diphenyl-2-thiohydantoin is employed in the synthetic routes leading to potential anti-cancer agents, highlighting its role in medicinal chemistry research.
| Molecular weight | 268.33 |
|---|---|
| Empirical formula | C15H12N2OS |
| Assay | 99% |
| Application | Reactant for synthesis of:• Imidazole derivatives1• Imidazothiazole and glycocyamidine derivatives for antimicrobial studies2• Fatty acid amide hydrolase inhibitor templates3• Anti-cancer agents4• Hydantoins and thiohydantoins5• Acyl CoA: cholesterol acyltransferase inhibitors6 |
| Melting point | 237-239 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CNR1(1268), CNR2(1269)rat ... Faah(29347) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5,5-Diphenyl-2-thiohydantoin used for?
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5,5-Diphenyl-2-thiohydantoin is used as a reactant in chemical synthesis for creating imidazole derivatives, imidazothiazole derivatives, fatty acid amide hydrolase inhibitor templates, anti-cancer agents, and acyl CoA: cholesterol acyltransferase inhibitors.
What are the CAS number and molecular formula for 5,5-Diphenyl-2-thiohydantoin?
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The CAS number for 5,5-Diphenyl-2-thiohydantoin is 21083-47-6, and its molecular formula is C15H12N2OS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5,5-Diphenyl-2-thiohydantoin with a minimum purity of 99% (Assay). This is a research-grade chemical and not intended for USP, BP, EP, or pharmaceutical use.
What are the safety considerations when handling 5,5-Diphenyl-2-thiohydantoin?
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5,5-Diphenyl-2-thiohydantoin is classified as harmful if swallowed, in contact with skin, or if inhaled (H302, H312, H332). It requires appropriate personal protective equipment including a dust mask (type N95), eyeshields, and gloves. Handle in a well-ventilated area.
How is 5,5-Diphenyl-2-thiohydantoin packed and shipped?
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5,5-Diphenyl-2-thiohydantoin is carefully packed to ensure safe transit and is exported globally by Tech Serve Solutions. Please contact us for specific shipping and handling details.
How can I request a sample or quote for 5,5-Diphenyl-2-thiohydantoin?
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To request a sample or a quote for 5,5-Diphenyl-2-thiohydantoin, please contact our sales department through the website or by phone, providing your specific requirements.
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