4α-Phorbol 12,13-didecanoate
4α-Phorbol 12,13-didecanoate (CAS: 27536-56-7) is a phorbol ester derivative with the molecular formula C40H64O8 and a molecular weight of 672.93 g/mol. It is supplied as a white solid, soluble in DMSO, ethanol, and methanol. Primarily used as a non-biologically active phorbol control in research settings, it aids in comparative studies and experimental validation within cell biology and signaling pathways.
- IUPAC
- 4α-Phorbol 12-13-dicaprinate,4αPDD
- Synonyms
- 4αPDD4α-Phorbol 12,13-dicaprinate
Negative Control in Biological Assays
Utilised as a control substance in experiments investigating phorbol ester activity. Its lack of biological activity allows researchers to establish baseline conditions and validate the specific effects of other active phorbol derivatives.
Research in Cell Signaling
Serves as a tool in cell biology and cell signaling research, particularly in studies involving protein kinase C (PKC) pathways. It helps elucidate the mechanisms of signal transduction without inducing cellular responses.
Chemical Reference Standard
Can be employed as a reference standard in analytical chemistry for the identification and quantification of related compounds. Its well-defined structure aids in method development and validation.
| Molecular weight | 672.93 |
|---|---|
| Empirical formula | C40H64O8 |
| Form | solid |
| Colour | white |
| Solubility | DMSO: solubleethanol: solublemethanol: soluble |
| Storage temperature | −20°C |
| Application | Phorbol that is not biologically active, can be used as a negative control. |
Hazard statements
- H300Fatal if swallowed
- H334May cause allergy or asthma symptoms if inhaled
- H351Suspected of causing cancer
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
- P302IF ON SKIN
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/27/28-40-43 |
| Safety statements (S) | 36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4α-Phorbol 12,13-didecanoate used for?
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4α-Phorbol 12,13-didecanoate is primarily used as a negative control in biological assays and research related to cell signaling, particularly in studies involving protein kinase C (PKC).
What are the CAS number and molecular formula for 4α-Phorbol 12,13-didecanoate?
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The CAS number for 4α-Phorbol 12,13-didecanoate is 27536-56-7, and its molecular formula is C40H64O8.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research purposes. The specific assay and purity are detailed on the product's Certificate of Analysis. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should 4α-Phorbol 12,13-didecanoate be handled safely?
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This compound is classified as Danger with severe hazards including acute toxicity (fatal if swallowed, in contact with skin, or if inhaled) and potential mutagenicity. Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges, is essential. Handle only in a well-ventilated area or under a fume hood. Consult the Safety Data Sheet (SDS) for comprehensive handling information.
How is 4α-Phorbol 12,13-didecanoate packed, shipped, and exported?
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This chemical is packed, shipped, and exported in compliance with relevant transportation regulations for hazardous materials, including UN 2811 classification. Storage is recommended at -20°C.
How can I request a sample or quote?
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To request a sample or quote for 4α-Phorbol 12,13-didecanoate, please contact our sales department via the website or listed phone number, providing your contact details and required quantity.
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