4-Nitro-2-(trifluoromethyl)benzoic acid
4-Nitro-2-(trifluoromethyl)benzoic acid (CAS: 320-37-6; C8H4F3NO4) is a specialised organic compound with a molecular weight of 235.12 g/mol. It is identified as a carboxylic acid and a carbonyl compound, featuring a nitro group and a trifluoromethyl substituent. This compound serves as a valuable building block in organic synthesis, particularly for creating more complex molecules in research and development settings. Its precise chemical structure makes it useful in various chemical transformations.

Organic Synthesis Intermediate
This benzoic acid derivative functions as a key intermediate in the synthesis of diverse organic compounds. Its functional groups allow for participation in various coupling and derivatisation reactions, facilitating the construction of complex molecular architectures.
Research and Development
Utilised in R&D laboratories for exploring new synthetic pathways and developing novel chemical entities. Its specific structure makes it suitable for applications in medicinal chemistry and materials science.
Building Block for Specialty Chemicals
Serves as a foundational component for the creation of specialty chemicals. The trifluoromethyl and nitro functionalities offer unique electronic and steric properties for targeted synthesis.
| Molecular weight | 235.12 |
|---|---|
| Empirical formula | C8H4F3NO4 |
| Assay | 97% |
| Melting point | 138-142 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36-43 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Nitro-2-(trifluoromethyl)benzoic acid used for?
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4-Nitro-2-(trifluoromethyl)benzoic acid is primarily used as a building block and intermediate in organic synthesis and research and development for creating complex organic molecules.
What is the CAS number and formula for 4-Nitro-2-(trifluoromethyl)benzoic acid?
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The CAS number is 320-37-6, and the molecular formula is C8H4F3NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Nitro-2-(trifluoromethyl)benzoic acid with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 4-Nitro-2-(trifluoromethyl)benzoic acid be handled safely?
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This compound is classified with GHS07 and the signal word Warning. It carries hazard statements H302 (Harmful if swallowed), H317 (May cause an allergic skin reaction), and H319 (Causes serious eye irritation). Appropriate personal protective equipment, including a dust mask type N95, eyeshields, faceshields, and gloves, should be used. Handle in a well-ventilated area.
Is 4-Nitro-2-(trifluoromethyl)benzoic acid exported by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Nitro-2-(trifluoromethyl)benzoic acid.
How can I request a quote or sample?
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To request a quote or sample of 4-Nitro-2-(trifluoromethyl)benzoic acid, please contact our sales department through the website or by phone, providing your specific requirements.
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