4-Fluoro-1,2-phenylenediamine
4-Fluoro-1,2-phenylenediamine (CAS 367-31-7) is an organic compound with the molecular formula C6H7FN2. This fluorinated aromatic diamine serves as a valuable building block in organic synthesis. Its structure, featuring both amine and fluorine functionalities, makes it suitable for the preparation of diverse heterocyclic compounds and complex molecules used in pharmaceuticals and materials science. Tech Serve Solutions offers this chemical for research and development purposes.
- IUPAC
- 1,2-Diamino-4-fluorobenzene,4-Fluoro-o-phenylenediamine
- Synonyms
- 1,2-Diamino-4-fluorobenzene4-Fluoro-o-phenylenediamine4-Fluoro-1,2-diaminobenzene

Pharmaceutical Intermediate Synthesis
Utilised as a key building block for the synthesis of various pharmaceutical agents. Its diamine structure allows for cyclization reactions, leading to heterocyclic scaffolds common in drug discovery.
Organic Synthesis Reagent
Serves as a versatile reagent in general organic synthesis. The presence of fluorine and two amine groups enables the construction of complex organic molecules with specific electronic and structural properties.
Material Science Applications
Can be employed in the development of novel materials, including polymers and functional dyes, where the fluorinated aromatic diamine structure can impart desirable characteristics.
| Molecular weight | 126.13 |
|---|---|
| Empirical formula | C6H7FN2 |
| Assay | ≥98.0% (GC) |
| Melting point | 91-95 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-1,2-phenylenediamine used for?
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4-Fluoro-1,2-phenylenediamine is primarily used as a building block in organic synthesis, particularly for the preparation of pharmaceuticals, heterocyclic compounds, and potentially in material science applications.
What is the CAS number and formula for 4-Fluoro-1,2-phenylenediamine?
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The CAS number for 4-Fluoro-1,2-phenylenediamine is 367-31-7, and its molecular formula is C6H7FN2. Its molecular weight is 126.13.
What grade and purity does Tech Serve Solutions supply for 4-Fluoro-1,2-phenylenediamine?
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Tech Serve Solutions supplies 4-Fluoro-1,2-phenylenediamine with a purity of ≥98.0% (GC). This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.
How should 4-Fluoro-1,2-phenylenediamine be handled safely?
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4-Fluoro-1,2-phenylenediamine is classified with GHS07 symbol and a Warning signal word. It is a skin irritant (H315), eye irritant (H319), and respiratory irritant (H335). Recommended personal protective equipment includes a dust mask type N95, eyeshields, and gloves. Handle in a well-ventilated area and avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes and remove contact lenses if present and easy to do. Continue rinsing.
Is 4-Fluoro-1,2-phenylenediamine a controlled substance?
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The provided safety data does not indicate that 4-Fluoro-1,2-phenylenediamine is a controlled substance.
How is 4-Fluoro-1,2-phenylenediamine packed and shipped?
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Products are packed and shipped according to international regulations for chemical transport. Please contact TSS for specific export and shipping details.
How can I request a quote or sample for 4-Fluoro-1,2-phenylenediamine?
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To request a quote or sample, please contact Tech Serve Solutions through our website or by direct inquiry, providing the product name and CAS number.
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