4-Ethynylbenzonitrile
4-Ethynylbenzonitrile (CAS: 3032-92-6; Formula: HC≡CC6H4CN; MW: 127.14) is a specialised organic compound featuring both a nitrile and a terminal alkyne functional group. This unique structure makes it a valuable building block in organic synthesis. It is primarily utilised in the development of advanced materials, pharmaceuticals, and agrochemicals through various coupling reactions and functional group transformations.
Organic Synthesis Intermediate
Serves as a key intermediate in the construction of complex organic molecules. The terminal alkyne can undergo Sonogashira coupling, click chemistry, and other alkyne-based reactions, while the nitrile group can be transformed into amines, amides, or carboxylic acids.
Materials Science Research
The rigid structure and reactive functional groups make it suitable for creating novel polymers, organic electronic materials, and supramolecular assemblies. It can be incorporated into conjugated systems for optoelectronic applications.
Pharmaceutical and Agrochemical Development
Used in the synthesis of biologically active compounds. The benzonitrile core and ethynyl substituent are common motifs found in various drug candidates and pesticides, enabling the exploration of new therapeutic or crop protection agents.
| Molecular weight | 127.14 |
|---|---|
| Linear formula | HC≡CC6H4CN |
| Assay | 97% |
| Melting point | 156-160 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Ethynylbenzonitrile used for?
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4-Ethynylbenzonitrile is used as a versatile building block in organic synthesis, particularly in the development of advanced materials, pharmaceuticals, and agrochemicals due to its reactive nitrile and alkyne functionalities.
What is the CAS number and chemical formula for 4-Ethynylbenzonitrile?
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The CAS number is 3032-92-6 and the chemical formula is HC≡CC6H4CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Ethynylbenzonitrile with an assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should 4-Ethynylbenzonitrile be handled safely?
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4-Ethynylbenzonitrile is classified as an irritant. Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust. Ensure good ventilation. If in eyes, rinse cautiously with water for several minutes; remove contact lenses if present and easy to do. Continue rinsing.
Is 4-Ethynylbenzonitrile available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals like 4-Ethynylbenzonitrile.
How can I request a quote or sample for 4-Ethynylbenzonitrile?
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Please contact our sales team through our website or by phone to request a quotation or a sample of 4-Ethynylbenzonitrile.
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