4-Chloro-3-(trifluoromethyl)benzaldehyde
4-Chloro-3-(trifluoromethyl)benzaldehyde (CAS: 34328-46-6) is a trifluoromethylated aromatic aldehyde with the chemical formula ClC6H3(CF3)CHO and a molecular weight of 208.56 g/mol. This compound functions as a valuable building block in organic synthesis. It is commonly employed in the preparation of more complex molecules, particularly within the pharmaceutical and agrochemical industries, owing to the presence of the reactive aldehyde group and the electron-withdrawing trifluoromethyl substituent.

Organic Synthesis Intermediate
Serves as a key intermediate in the synthesis of diverse organic compounds. The aldehyde functionality allows for various nucleophilic addition and condensation reactions, while the trifluoromethyl group imparts unique electronic properties to downstream products.
Pharmaceutical Building Block
Utilised in the development of novel pharmaceutical agents. Its structure is amenable to incorporation into heterocyclic systems and other drug scaffolds, potentially influencing biological activity and pharmacokinetic profiles.
Agrochemical Research
Applied in the research and development of new agrochemicals. The presence of the trifluoromethyl moiety is often associated with enhanced efficacy and metabolic stability in pesticides and herbicides.
| Molecular weight | 208.56 |
|---|---|
| Linear formula | ClC6H3(CF3)CHO |
| Assay | 97% |
| Boiling point | 218 °C(lit.) |
| Density | 1.45 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.504(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-3-(trifluoromethyl)benzaldehyde used for?
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4-Chloro-3-(trifluoromethyl)benzaldehyde is primarily used as an intermediate and building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals.
What is the CAS number and chemical formula for 4-Chloro-3-(trifluoromethyl)benzaldehyde?
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The CAS number is 34328-46-6 and the chemical formula is ClC6H3(CF3)CHO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chloro-3-(trifluoromethyl)benzaldehyde with a minimum assay of 97%. This product is intended for laboratory and research use; TSS does not represent it as USP, BP, EP, or any other pharmacopoeial grade.
How should 4-Chloro-3-(trifluoromethyl)benzaldehyde be handled safely?
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This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator. Ensure adequate ventilation.
Is 4-Chloro-3-(trifluoromethyl)benzaldehyde exported globally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Chloro-3-(trifluoromethyl)benzaldehyde.
How can I request a quote or sample?
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To request a quote or sample of 4-Chloro-3-(trifluoromethyl)benzaldehyde, please contact our sales department via the website or direct email, providing your specific requirements.
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