4-Chloro-2-phenylquinazoline
4-Chloro-2-phenylquinazoline (CAS 6484-25-9, C14H9ClN2) is a halogenated heterocyclic building block with a molecular weight of 240.69 g/mol. This compound serves as a valuable intermediate in organic synthesis, particularly for the creation of complex molecules within the pharmaceutical and chemical research sectors. Its utility is demonstrated in the synthesis of various ligands and complex amines, making it a key component for advanced chemical applications.
- IUPAC
- AM-ex-OL®,NSC 400965
Synthesis of Ligands
Utilised in the preparation of novel axially chiral quinazoline-containing phosphinamine ligands, crucial for asymmetric catalysis research.
Intermediate for Amine Synthesis
Acts as a precursor in the synthesis of N,N,2-triphenylquinazolin-4-amine, a complex organic molecule.
Heterocyclic Compound Synthesis
Employed in the synthesis of sulfanyl and sulfinylbenzodiazines, contributing to the development of new heterocyclic compounds.
Reagent for Phenol to Aniline Conversion
Serves as a key reagent in established chemical transformations, specifically for converting phenols into anilines.
| Molecular weight | 240.69 |
|---|---|
| Empirical formula | C14H9ClN2 |
| Assay | 97% |
| Application | 4-Chloro-2-phenylquinazoline was used in synthesis of axially chiral quinazoline-containing phosphinamine ligand1, N,N,2-triphenylquinazolin-4-amine2, sulfanyl and sulfinylbenzodiazines3. It was used as reagent for the conversion of phenols to anilines4,5. |
| Melting point | 124-126 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-2-phenylquinazoline used for?
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4-Chloro-2-phenylquinazoline is primarily used as a building block in chemical synthesis, including the preparation of ligands, amines, and other complex heterocyclic compounds, and as a reagent for converting phenols to anilines.
What are the CAS number and formula for 4-Chloro-2-phenylquinazoline?
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The CAS number is 6484-25-9, and the empirical formula is C14H9ClN2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chloro-2-phenylquinazoline with a minimum purity of 97%. This product is supplied for research and laboratory use and is not represented as USP, EP, BP, or pharmaceutical grade.
How should 4-Chloro-2-phenylquinazoline be handled safely?
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4-Chloro-2-phenylquinazoline is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including gloves, eye protection, and ensure adequate ventilation. Avoid breathing dust.
How is 4-Chloro-2-phenylquinazoline packed and shipped?
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This chemical is carefully packed in compliance with international shipping regulations and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for 4-Chloro-2-phenylquinazoline?
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To request a sample or obtain a quotation, please contact our sales team via the website or by phone. Provide your contact details and the quantity required.
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