4-Bromothiophene-3-carbonitrile
4-Bromothiophene-3-carbonitrile (CAS: 18895-10-8) is a key heterocyclic building block with the molecular formula C5H2BrNS and a molecular weight of 188.05 g/mol. This compound is valued in organic synthesis for its thiophene core and reactive bromine and nitrile functionalities. It serves as an intermediate in the development of novel materials and active pharmaceutical ingredients. Tech Serve Solutions provides this chemical with a minimum assay of 97%.
- IUPAC
- 4-Bromo-3-cyanothiophene
- Synonyms
- 4-Bromo-3-cyanothiophene

Organic Synthesis Intermediate
Utilised as a versatile building block in the construction of more complex organic molecules. Its bromo- and cyano- substituents allow for a range of cross-coupling and functional group interconversion reactions.
Pharmaceutical Research
Incorporated into synthetic pathways for the development of potential pharmaceutical agents. The thiophene moiety is a common feature in many biologically active compounds.
Materials Science
Applied in the synthesis of functional organic materials, potentially including organic semiconductors and dyes, owing to the electronic properties of the thiophene ring.
| Molecular weight | 188.05 |
|---|---|
| Empirical formula | C5H2BrNS |
| Assay | 97% |
| Melting point | 58-62 °C |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41-43 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromothiophene-3-carbonitrile used for?
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4-Bromothiophene-3-carbonitrile is primarily used as a building block in organic synthesis, particularly for the preparation of pharmaceuticals and advanced materials. Its reactive functional groups facilitate the creation of complex molecular structures.
What are the CAS number and molecular formula for 4-Bromothiophene-3-carbonitrile?
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The CAS number is 18895-10-8 and the molecular formula is C5H2BrNS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromothiophene-3-carbonitrile with a minimum assay of 97%. This compound is not represented as USP, BP, EP, or any pharmacopoeia grade.
What are the safety considerations for handling 4-Bromothiophene-3-carbonitrile?
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This compound is classified as Danger. It is harmful if swallowed (H302), causes skin irritation (H315), may cause an allergic skin reaction (H317), causes serious eye damage (H318), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including gloves, eye protection, and ensure adequate ventilation.
How is 4-Bromothiophene-3-carbonitrile shipped?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and can fulfil export orders for 4-Bromothiophene-3-carbonitrile.
How can I request a quote or sample for 4-Bromothiophene-3-carbonitrile?
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Please contact our sales team via the website or telephone to request a quote or sample of 4-Bromothiophene-3-carbonitrile.
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