[4-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution
[4-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution (CAS 480424-78-0) is an organometallic reagent supplied by TSS. With a molecular weight of 264.44 g/mol, this Grignard reagent is prepared as a 0.25 M solution in THF. It is utilized in chemical synthesis as a valuable building block for introducing functionalized aryl groups in complex molecule construction, particularly in pharmaceutical and fine chemical research and development.
![[4-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution (C6H4CH2NC4H8MgBr) — chemical structure, CAS 480424-78-0; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F480424-78-0.png&w=3840&q=75)
Aryl Group Introduction
This Grignard reagent serves as a potent nucleophile for the synthesis of carbon-carbon bonds. It is employed to introduce the 4-(1-pyrrolidinylmethyl)phenyl moiety into various organic substrates, facilitating the construction of complex molecular architectures.
Pharmaceutical Intermediate Synthesis
The compound is instrumental in the development of novel pharmaceutical agents. Its ability to readily react with electrophiles makes it a key intermediate in multi-step synthetic routes targeting biologically active molecules.
Fine Chemical Manufacturing
Utilized in the broader fine chemical industry, this organometallic reagent enables the efficient synthesis of specialised chemicals with precise structural requirements.
| Molecular weight | 264.44 |
|---|---|
| Linear formula | C6H4CH2NC4H8MgBr |
| Boiling point | 65 °C |
| Density | 0.916 g/mL at 25 °C |
| Concentration | 0.25 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37/38-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is [4-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution used for?
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This Grignard reagent is primarily used in chemical synthesis for introducing the 4-(1-pyrrolidinylmethyl)phenyl group into organic molecules. It is particularly useful in the synthesis of pharmaceutical intermediates and fine chemicals.
What is the CAS number and formula for this compound?
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The CAS number is 480424-78-0. The linear formula is C6H4CH2NC4H8MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.25 M solution in THF. We do not claim USP, BP, or EP grade unless explicitly stated in the product data. For detailed specifications, please refer to the product data sheet.
How should [4-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution be handled?
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This compound is highly flammable and corrosive. It reacts violently with water and can form explosive peroxides. Handle in a well-ventilated area, away from ignition sources, and use appropriate personal protective equipment, including gloves, eye protection, and protective clothing. Refer to the Safety Data Sheet for detailed handling and storage instructions.
How is this chemical shipped and exported?
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This product is shipped and exported under UN 2924, Hazard Class 8(3), Packing Group II, due to its corrosive and flammable nature. TSS adheres to all international regulations for the safe transport of hazardous chemicals.
How can I request a sample or quote?
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To request a sample or a quote for [4-(1-Pyrrolidinylmethyl)phenyl]magnesium bromide solution, please contact our sales team via the website or by phone, providing your details and the product's CAS number (480424-78-0).
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