3-(Methanesulfonylamino)phenylboronic acid pinacol ester
3-(Methanesulfonylamino)phenylboronic acid pinacol ester (CAS: 305448-92-4), with the molecular formula C13H20BNO4S and a molecular weight of 297.18, is a key organometallic reagent. It serves as a versatile building block in organic synthesis, particularly in the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. Its structured functionality makes it valuable in the development of pharmaceuticals and advanced materials.
- IUPAC
- N-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanesulfonamide
- Synonyms
- N-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanesulfonamide
Suzuki-Miyaura Cross-Coupling
This boronate ester is extensively employed as a coupling partner in Suzuki-Miyaura reactions, enabling the efficient synthesis of biaryl compounds and other complex organic molecules.
Pharmaceutical Intermediate Synthesis
Its utility extends to the preparation of active pharmaceutical ingredients (APIs) and complex intermediates, leveraging its arylboronic acid ester structure for targeted molecular assembly.
Materials Science
The compound can be utilised in the development of novel organic materials with specific electronic or optical properties, often incorporated into conjugated systems.
Organic Synthesis Building Block
As a functionalised arylboronic acid derivative, it provides a reliable route for introducing the methanesulfonylaminophenyl moiety into diverse molecular scaffolds.
| Molecular weight | 297.18 |
|---|---|
| Empirical formula | C13H20BNO4S |
| Assay | 97% |
| Melting point | 153-157 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Methanesulfonylamino)phenylboronic acid pinacol ester used for?
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This compound is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, and in the preparation of pharmaceutical intermediates and novel organic materials.
What are the CAS number and formula for this chemical?
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The CAS number is 305448-92-4 and the empirical formula is C13H20BNO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a purity of 97%. This is a technical/research grade material, and we do not represent it as meeting USP, BP, or EP pharmacopoeial standards.
What are the safety precautions for handling this compound?
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This compound is classified as harmful if swallowed (H302). When handling, use a dust mask type N95 (US), wear eyeshields, and use gloves. Ensure adequate ventilation. Store in a cool, dry place.
How is this chemical shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. This product is carefully packaged according to international shipping regulations and exported worldwide.
How can I request a sample or a quote for 3-(Methanesulfonylamino)phenylboronic acid pinacol ester?
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To request a sample or a quote, please contact our sales department through the website or call us directly. Please provide the product name and CAS number (305448-92-4).
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