3-Chloro-5-fluorophenylmagnesium bromide solution
3-Chloro-5-fluorophenylmagnesium bromide solution (CAS: 480438-50-4) is an organometallic compound with the linear formula ClC 6 3(F)MgBr and a molecular weight of 233.75 g/mol. Supplied at 0.5 M in THF, this Grignard reagent is a valuable building block in organic synthesis for introducing the 3-chloro-5-fluorophenyl moiety into complex molecules. Its applications are primarily within chemical research and development, facilitating the creation of novel compounds.
Grignard Reagent in Organic Synthesis
Serves as a nucleophilic coupling partner for reactions with electrophiles such as aldehydes, ketones, and esters. Enables the formation of carbon-carbon bonds for constructing more complex molecular architectures.
Arylating Agent
Used to introduce the 3-chloro-5-fluorophenyl group into target molecules. This functionalised aryl halide is crucial in the synthesis of various speciality chemicals and advanced intermediates.
Research and Development
Essential reagent for academic and industrial laboratories exploring new synthetic routes and developing novel compounds with specific electronic or steric properties.
| Molecular weight | 233.75 |
|---|---|
| Linear formula | ClC6H3(F)MgBr |
| Boiling point | 65 °C |
| Density | 0.968 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloro-5-fluorophenylmagnesium bromide solution used for?
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This compound is primarily used as a Grignard reagent in organic synthesis to introduce the 3-chloro-5-fluorophenyl group into target molecules, facilitating the construction of complex chemical structures in research and development settings.
What are the CAS number and formula for this compound?
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The CAS number is 480438-50-4 and the linear formula is ClC 6 3(F)MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.5 M solution in Tetrahydrofuran (THF). We do not specify pharmaceutical or other compendial grades unless explicitly stated, and do not represent this product as USP, BP, or EP grade.
How should 3-Chloro-5-fluorophenylmagnesium bromide solution be handled and stored?
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This is a highly flammable liquid and vapour (H225). It can cause serious eye irritation (H319) and may cause respiratory irritation (H335). It is also suspected of causing cancer (H351). Handle in a well-ventilated area, away from ignition sources. Store at 2-8°C. May form explosive peroxides.
Is this chemical suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and reagents. This product can be packed and shipped internationally in compliance with relevant regulations.
How can I request a quote or sample?
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Please contact our sales team or use the online inquiry form to request a quote or sample for 3-Chloro-5-fluorophenylmagnesium bromide solution.
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