3-Butyn-2-one
3-Butyn-2-one (CAS 1423-60-5) is a versatile organic compound with the linear formula HC≡CCOCH₃ and a molecular weight of 68.07 g/mol. This ketone is a valuable building block in chemical synthesis, particularly recognised for its utility in creating more complex organic structures. Its reactive alkyne and carbonyl functionalities make it a useful intermediate in various organic transformations.
Organic Synthesis Intermediate
3-Butyn-2-one serves as a key building block in the synthesis of complex organic molecules. It is employed in reactions such as stereoselective conjugate arylation to form α,β-unsaturated ketones.
Diterpenoid Synthesis
This compound has been utilised in the synthesis of natural products, including clerodane diterpenoids like (+/-)-sacacarin, highlighting its role in complex molecule construction.
Preparation of Unsaturated Ketones
It acts as a substrate in reactions designed to produce α,β-unsaturated ketones, offering a route to valuable carbonyl compounds with specific stereochemistry.
| Molecular weight | 68.07 |
|---|---|
| Linear formula | HC≡CCOCH3 |
| Assay | 95% |
| Boiling point | 85 °C(lit.) |
| Density | 0.87 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.406(lit.) |
| Application | 3-Butyn-2-one was used in the synthesis of clerodane diterpenoid (+/-)-sacacarin. It was used as substrate in stereoselective, conjugate arylation mediated by gallium(III) chloride leading to (E)-α,β-unsaturated ketones1. |
Hazard statements
- H225Highly flammable liquid and vapour
- H300Fatal if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P264Wash thoroughly after handling
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -1 °C / 30.2 °F |
| Transport (UN / ADR) | UN 1992 3/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,T+ |
| Risk statements (R) | 11-28-36/37/38 |
| Safety statements (S) | 7/9-16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Butyn-2-one used for?
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3-Butyn-2-one is primarily used as a building block in organic synthesis, including the preparation of clerodane diterpenoids and stereoselective synthesis of α,β-unsaturated ketones.
What are the CAS number and formula for 3-Butyn-2-one?
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The CAS number for 3-Butyn-2-one is 1423-60-5, and its linear formula is HC≡CCOCH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Butyn-2-one with an assay of 95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-Butyn-2-one be handled safely?
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3-Butyn-2-one is a highly flammable liquid and vapour (H225) and is acutely toxic if swallowed (H300). It also causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handling requires appropriate personal protective equipment, including eyeshields, faceshields, gloves, and suitable respiratory protection.
How is 3-Butyn-2-one packed, shipped, and exported?
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3-Butyn-2-one is carefully packed according to international shipping regulations for hazardous materials, including UN 1992 classification. Tech Serve Solutions exports globally.
How can I request a quote or sample of 3-Butyn-2-one?
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Please contact our sales team via our website or direct email to request a quote or a sample of 3-Butyn-2-one, providing your specific requirements.
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