3′-Bromo-5′-chloro-2′-hydroxyacetophenone
3′-Bromo-5′-chloro-2′-hydroxyacetophenone (CAS 59443-15-1), a substituted acetophenone with the molecular formula ClC<sub>6</sub>H<sub>2</sub>(Br)(OH)COCH<sub>3</sub> and a molecular weight of 249.49 g/mol, serves as a valuable building block in organic synthesis. Its carefully arranged functional groups, including ketone, phenol, and halogen substituents, make it a versatile intermediate for the creation of more complex molecules. This compound is primarily utilised in chemical research and development.
- IUPAC
- 1-(3-Bromo-5-chloro-2-hydroxyphenyl)ethanone,5-Chloro-3-bromo-2-hydroxyacetophenone
- Synonyms
- 1-(3-Bromo-5-chloro-2-hydroxyphenyl)ethanone5-Chloro-3-bromo-2-hydroxyacetophenone

Organic Synthesis Intermediate
This compound is a key intermediate in the synthesis of various organic molecules. The presence of bromine, chlorine, and hydroxyl groups on the aromatic ring allows for diverse chemical transformations.
Research and Development
Utilised in R&D laboratories for exploring new synthetic pathways and developing novel compounds, particularly within the realms of medicinal chemistry and materials science.
Building Block for Heterocycles
The acetophenone structure, with its reactive carbonyl and substituted phenyl ring, makes it suitable for constructing heterocyclic compounds which are prevalent in pharmaceuticals and agrochemicals.
| Molecular weight | 249.49 |
|---|---|
| Linear formula | ClC6H2(Br)(OH)COCH3 |
| Assay | 97% |
| Melting point | 100-103 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3′-Bromo-5′-chloro-2′-hydroxyacetophenone used for?
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3′-Bromo-5′-chloro-2′-hydroxyacetophenone is primarily used as a building block and intermediate in organic synthesis and chemical research and development.
What is the CAS number and molecular formula for 3′-Bromo-5′-chloro-2′-hydroxyacetophenone?
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The CAS number is 59443-15-1, and its linear formula is ClC<sub>6</sub>H<sub>2</sub>(Br)(OH)COCH<sub>3</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3′-Bromo-5′-chloro-2′-hydroxyacetophenone with an assay of 97%. TSS does not represent this product as USP, BP, or EP grade; it is supplied for research and laboratory use.
How should 3′-Bromo-5′-chloro-2′-hydroxyacetophenone be handled safely?
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This compound is a Warning product (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate PPE, including a dust mask (type N95 US), eyeshields, and gloves. Ensure good ventilation and avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes (P305 + P351 + P338).
How is 3′-Bromo-5′-chloro-2′-hydroxyacetophenone packed, shipped, and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging and documentation for the safe and compliant shipment of chemicals worldwide, adhering to international shipping regulations.
How can I request a sample or quote for this chemical?
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To request a sample or a quote, please contact our sales department via the website or by phone, providing the product name and CAS number (59443-15-1).
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