(2R,3S)-(−)-N-Boc-6-oxo-2,3-diphenylmorpholine
(2R,3S)-(−)-N-Boc-6-oxo-2,3-diphenylmorpholine (CAS: 112741-49-8) is a chiral building block with the molecular formula C21H23NO4 and a molecular weight of 353.41 g/mol. This morpholine derivative is a key intermediate in asymmetric synthesis and heterocyclic chemistry. It is supplied with a minimum assay of 98% and is typically stored at 2-8°C to maintain its integrity for sophisticated chemical research and development.
- IUPAC
- tert-Butyl (2R,3S)-(−)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
- Synonyms
- 112741-49-8C21H23NO4tert-Butyl (2R,3S)-(−)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate

Chiral Building Block in Asymmetric Synthesis
This compound serves as a valuable chiral precursor in the construction of complex stereodefined molecules. Its specific stereochemistry is crucial for developing enantiomerically pure target compounds in pharmaceutical and fine chemical research.
Heterocyclic Chemistry Intermediate
As a substituted morpholine, it is employed in the synthesis of various heterocyclic compounds. Its unique structural features can be leveraged to introduce specific functionalities and stereochemical control into larger molecular frameworks.
Research and Development Reagent
This chemical is utilised in academic and industrial research laboratories for exploring novel synthetic pathways and developing new chemical entities. Its well-defined chiral centres make it ideal for stereoselective reactions.
| Molecular weight | 353.41 |
|---|---|
| Empirical formula | C21H23NO4 |
| Assay | 98% |
| Optical activity | [α]25/D −87°, c = 5.5 in methylene chloride |
| Optical purity | ee: 99% (HPLC) |
| Storage temperature | 2-8°C |
| Melting point | 206 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2R,3S)-(−)-N-Boc-6-oxo-2,3-diphenylmorpholine used for?
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(2R,3S)-(−)-N-Boc-6-oxo-2,3-diphenylmorpholine is used as a chiral building block in asymmetric synthesis and as an intermediate in heterocyclic chemistry for research and development purposes.
What is the CAS number and molecular formula for this compound?
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The CAS number is 112741-49-8 and the molecular formula is C21H23NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with a minimum assay of 98%. We do not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should (2R,3S)-(−)-N-Boc-6-oxo-2,3-diphenylmorpholine be handled and stored?
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This compound is a warning substance (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment including a dust mask (N95), eyeshields, and gloves. Store at 2-8°C.
How is this chemical shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates and laboratory reagents, ensuring appropriate packaging and documentation for international shipments.
How can I request a sample or quote for this product?
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Please contact our sales team directly through our website or by phone to request a sample or a quotation for (2R,3S)-(−)-N-Boc-6-oxo-2,3-diphenylmorpholine.
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