20-Deoxy-20-oxophorbol 12,13-dibutyrate
20-Deoxy-20-oxophorbol 12,13-dibutyrate (CAS: 100930-03-8; C28H38O8) is a complex organic compound with a molecular weight of 502.60. This phorbol derivative is primarily utilised in biochemical research. Its key application involves reduction with tritiated sodium borohydride to yield tritiated phorbol 12,13-dibutyrate, a crucial radioligand for investigating receptor binding interactions and cellular signalling pathways.
- IUPAC
- PDBuAL
- Synonyms
- Phorbol 12,13-dibutyrate 20-aldehyde, PDBuAL
Radioligand Synthesis
Reduction of 20-Deoxy-20-oxophorbol 12,13-dibutyrate with tritiated sodium borohydride produces tritiated phorbol 12,13-dibutyrate. This radiolabelled compound is essential for conducting receptor binding studies.
Biochemical Research Tool
As a phorbol ester derivative, this compound serves as a valuable tool in biochemical and pharmacological research. It aids in understanding protein kinase C (PKC) pathways and cellular responses.
Organic Synthesis Intermediate
The structure of 20-Deoxy-20-oxophorbol 12,13-dibutyrate makes it a useful building block in complex organic synthesis projects, particularly within medicinal chemistry research.
| Molecular weight | 502.60 |
|---|---|
| Empirical formula | C28H38O8 |
| Storage temperature | −20°C |
| Application | Reduction with tritiated NaBH4 yields tritiated phorbol 12,13-dibutyrate that can be used for receptor binding studies |
Hazard statements
- H300Fatal if swallowed
- H310Fatal in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H330Fatal if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P302IF ON SKIN
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/27/28-36/37/38 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 20-Deoxy-20-oxophorbol 12,13-dibutyrate used for?
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20-Deoxy-20-oxophorbol 12,13-dibutyrate is used for the synthesis of radiolabelled phorbol 12,13-dibutyrate for receptor binding studies and as a building block in organic synthesis for biochemical research.
What is the CAS number and molecular formula for 20-Deoxy-20-oxophorbol 12,13-dibutyrate?
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The CAS number is 100930-03-8 and the molecular formula is C28H38O8.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and laboratory use. The specific assay and purity details are available on the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
How should 20-Deoxy-20-oxophorbol 12,13-dibutyrate be handled safely?
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This compound is classified as acutely toxic (Danger, H300, H310, H330) and is a skin and eye irritant (H315, H319, H335). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection (N100 or P1/P3 filters), must be used. Handle in a well-ventilated area or fume hood.
Is 20-Deoxy-20-oxophorbol 12,13-dibutyrate a controlled substance?
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The provided safety data does not indicate that 20-Deoxy-20-oxophorbol 12,13-dibutyrate is a controlled substance.
How is this chemical packed and shipped?
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20-Deoxy-20-oxophorbol 12,13-dibutyrate is typically stored at -20°C. Shipments are handled according to international regulations for hazardous materials, including UN 2811 classification (Toxic solid, organic, n.o.s.).
How can I request a sample or a quote?
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Please contact our sales team through the website or by email to request a sample or a quotation for 20-Deoxy-20-oxophorbol 12,13-dibutyrate.
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