2-Pyrrolidone-5-carboxylic acid
2-Pyrrolidone-5-carboxylic acid (CAS: 149-87-1, C5H7NO3) is a chemical compound with a molecular weight of 129.11 g/mol. This substance is a derivative of pyrrolidone and finds utility in various chemical processes. It is employed in chemical synthesis and biochemical research, serving as a building block or intermediate in the development of more complex molecules. Its applications span across peptide chemistry and the study of unnatural amino acid derivatives.
- IUPAC
- DL-5-Oxo-2-pyrrolidinecarboxylic acid,DL-Pyroglutamic acid
- Synonyms
- DL-5-Oxo-2-pyrrolidinecarboxylic acidDL-Pyroglutamic acid

Chemical Synthesis
Utilised as an intermediate or building block in the synthesis of complex organic molecules. Its structure lends itself to various reactions in synthetic organic chemistry.
Peptide Chemistry
Serves as a component in the synthesis and modification of peptides. It can be incorporated into peptide chains or used in derivatisation processes.
Biochemical Research
Applied in studies within chemical biology, particularly in the investigation of unnatural amino acid derivatives and their biological roles.
| Molecular weight | 129.11 |
|---|---|
| Empirical formula | C5H7NO3 |
| Assay | 99% |
| Melting point | 183-185 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Pyrrolidone-5-carboxylic acid used for?
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2-Pyrrolidone-5-carboxylic acid is used in chemical synthesis, peptide chemistry, and biochemical research, including studies involving unnatural amino acid derivatives.
What are the CAS number and formula for 2-Pyrrolidone-5-carboxylic acid?
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The CAS number is 149-87-1 and the empirical formula is C5H7NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Pyrrolidone-5-carboxylic acid with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
What are the primary hazards associated with 2-Pyrrolidone-5-carboxylic acid?
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This compound is classified with the GHS symbol GHS07 and is a Warning. It carries hazard statements including H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment such as a dust mask (type N95), eyeshields, and gloves should be used.
How is 2-Pyrrolidone-5-carboxylic acid packed and shipped?
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2-Pyrrolidone-5-carboxylic acid is packed and shipped according to industry best practices for chemical compounds, ensuring safe transport and export globally by TSS.
How can I request a sample or quote for 2-Pyrrolidone-5-carboxylic acid?
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To request a sample or a quote, please use the contact form on our website or contact our sales department directly. Please reference product code 149-87-1.
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