2-Nitro-5-pyridineboronic acid pinacol ester
2-Nitro-5-pyridineboronic acid pinacol ester (CAS: 1073371-93-3) is an organoboron compound with the molecular formula C11H15BN2O4 and a molecular weight of 250.06 g/mol. As a heteroaryl boronate ester, it serves as a versatile building block in organic synthesis, particularly in cross-coupling reactions. Its structure allows for the introduction of a nitropyridine moiety into complex molecules, making it valuable in pharmaceutical research and fine chemical production.
- IUPAC
- 2-Nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Suzuki-Miyaura Cross-Coupling Reactions
This boronate ester is a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds. It is used to introduce the 2-nitro-5-pyridyl group onto various organic scaffolds.
Pharmaceutical Intermediate Synthesis
Its utility as a building block makes it important in the synthesis of complex heterocyclic compounds relevant to pharmaceutical research and development. The nitropyridine motif is present in various biologically active molecules.
Materials Science Research
Heteroaryl boronate esters can be employed in the development of novel organic materials, such as those used in organic electronics or advanced polymers, though specific applications for this compound are not detailed.
Agrochemical Synthesis
The structural features of nitropyridines are found in certain agrochemical compounds, suggesting potential applications in the synthesis of pesticides or herbicides.
| Molecular weight | 250.06 |
|---|---|
| Empirical formula | C11H15BN2O4 |
| Assay | 97% |
| Melting point | 155-159 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Nitro-5-pyridineboronic acid pinacol ester used for?
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2-Nitro-5-pyridineboronic acid pinacol ester is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions to introduce a 2-nitro-5-pyridyl group into molecules. It finds applications in pharmaceutical intermediate synthesis and potentially in materials science and agrochemical research.
What are the CAS number and chemical formula?
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The CAS number is 1073371-93-3, and the chemical formula is C11H15BN2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with a typical assay of 97%. It is supplied for research and laboratory use, and TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should 2-Nitro-5-pyridineboronic acid pinacol ester be handled safely?
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This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). When handling, wear a dust mask (type N95 or equivalent), safety eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes (P305 + P351 + P338).
Is this chemical a controlled substance?
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The provided data does not indicate that 2-Nitro-5-pyridineboronic acid pinacol ester is a controlled substance.
How is this chemical packed and shipped?
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As a global supplier and exporter, Tech Serve Solutions ensures appropriate packaging for chemical stability and safe transport. Specific packaging details are confirmed upon order, and shipments comply with international regulations.
How can I request a sample or quote?
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To request a sample or a quote, please use the 'Contact Us' form on the Tech Serve Solutions website or call our sales team. Please provide the product name and CAS number (1073371-93-3) for faster service.
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