2-Methoxypropene
2-Methoxypropene (CAS: 116-11-0), with the chemical formula CH2=C(CH3)OCH3 and a molecular weight of 72.11 g/mol, is a valuable reagent in organic synthesis. It is primarily utilised for the protection of adjacent hydroxyl groups, notably in inositols to form bisacetonides, and for the derivatisation of 1,2-diols. Its specific reactivity makes it an important tool in multi-step chemical processes.
- IUPAC
- Isopropenyl methyl ether
- Synonyms
- Isopropenyl methyl ether

Protection of Hydroxyl Groups
2-Methoxypropene serves as an effective reagent for protecting adjacent hydroxyl functionalities in molecules such as inositols, forming stable bisacetonide derivatives. This protection strategy is crucial in multi-step synthesis to prevent unwanted side reactions.
Derivatisation of Diols
This compound is employed for the derivatisation of 1,2-diols. By reacting with these vicinal diols, it facilitates their modification, which can be useful for analytical purposes or for directing further chemical transformations.
Synthetic Reagent
As a versatile synthetic reagent, 2-Methoxypropene is used in various organic synthesis pathways. Its role in protecting functional groups aids in complex molecule construction and fine chemical production.
| Molecular weight | 72.11 |
|---|---|
| Linear formula | CH2=C(CH3)OCH3 |
| Assay | 97% |
| Boiling point | 34-36 °C(lit.) |
| Density | 0.753 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.382(lit.) |
| Vapour pressure | 27.96 psi (55 °C)8.28 psi (20 °C) |
| Autoignition temp | 374 °F |
| Storage temperature | 2-8°C |
| Application | Used to protect adjacent hydroxyls in inositols as bisacetonides,1 and 1,2-diols in general.2 |


Hazard statements
- H224Extremely flammable liquid and vapour
- H302Harmful if swallowed
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | -29 °C / -20.2 °F |
| Transport (UN / ADR) | UN 1993A 3 / PGI |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F+,Xn |
| Risk statements (R) | 12-19-22 |
| Safety statements (S) | 3-7/9-16-29-33 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methoxypropene used for?
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2-Methoxypropene is used to protect adjacent hydroxyl groups in molecules like inositols, forming bisacetonides, and is also used for the derivatisation of 1,2-diols in organic synthesis.
What is the CAS number and formula for 2-Methoxypropene?
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The CAS number for 2-Methoxypropene is 116-11-0, and its chemical formula is CH2=C(CH3)OCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Methoxypropene with an assay of 97%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Methoxypropene be handled safely?
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2-Methoxypropene is highly flammable (H224) and harmful if swallowed (H302). It may also form explosive peroxides. Handle in a well-ventilated area, away from ignition sources, and wear appropriate personal protective equipment including eyeshields, gloves, and a suitable respirator.
How is 2-Methoxypropene packed, shipped, and exported?
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2-Methoxypropene is stored at 2-8°C. Shipping and export are handled in accordance with all applicable international regulations for hazardous materials, including flammable liquids.
How can I request a sample or a quote for 2-Methoxypropene?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
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