2-Hydroxy-3-methoxybenzoic acid
2-Hydroxy-3-methoxybenzoic acid (CAS 877-22-5) is an organic compound with the formula CH3OC6H3(OH)CO2H and a molecular weight of 168.15 g/mol. This carboxylic acid derivative serves as a valuable building block in organic synthesis. It is utilized in the preparation of more complex molecules, including pharmaceutical intermediates. Its specific structure makes it suitable for various chemical transformations.
- IUPAC
- 3-Methoxysalicylic acid
Internal Standard in Chromatography
2-Hydroxy-3-methoxybenzoic acid has been employed as an internal standard for the precise quantification of acetylsalicylic acid and its metabolite, salicylic acid, in human plasma using high-performance liquid chromatography.
Synthesis of Heterocyclic Compounds
This compound has been utilised in the large-scale synthesis of 7-methoxy-3(2H)-benzofuranone, a key step in the production of various organic molecules.
Organic Building Block
As a versatile organic building block, it is used in diverse chemical synthesis routes. Its functional groups allow for various reactions, contributing to the creation of novel compounds.
| Molecular weight | 168.15 |
|---|---|
| Linear formula | CH3OC6H3(OH)CO2H |
| Assay | 97% |
| Application | 2-Hydroxy-3-methoxybenzoic acid was used as internal standard during the simultaneous quantification of acetylsalicylic acid and its metabolite salicylic acid in human plasma by high-performance liquid chromatography1. It was used in large-scale synthesis of 7-methoxy-3(2H)-benzofuranone2. |
| Melting point | 147-150 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Hydroxy-3-methoxybenzoic acid used for?
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2-Hydroxy-3-methoxybenzoic acid is used as an internal standard in analytical chemistry, particularly in high-performance liquid chromatography for drug metabolite quantification. It also serves as a building block in organic synthesis, for example, in the production of 7-methoxy-3(2H)-benzofuranone.
What are the CAS number and chemical formula for 2-Hydroxy-3-methoxybenzoic acid?
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The CAS number for 2-Hydroxy-3-methoxybenzoic acid is 877-22-5, and its chemical formula is CH3OC6H3(OH)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Hydroxy-3-methoxybenzoic acid with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for 2-Hydroxy-3-methoxybenzoic acid?
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2-Hydroxy-3-methoxybenzoic acid is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with a dust mask type N95 (US), eyeshields, and gloves. Ensure good ventilation and avoid breathing dust. In case of contact with eyes, rinse cautiously with water for several minutes.
Is 2-Hydroxy-3-methoxybenzoic acid a controlled substance?
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Based on the provided data, 2-Hydroxy-3-methoxybenzoic acid is not listed as a controlled substance.
How is 2-Hydroxy-3-methoxybenzoic acid packed and shipped?
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2-Hydroxy-3-methoxybenzoic acid is carefully packed for safe transport, adhering to all relevant regulations for chemical exports. Specific packing details can be provided upon request.
How can I request a quote or sample for 2-Hydroxy-3-methoxybenzoic acid?
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To request a quote or sample of 2-Hydroxy-3-methoxybenzoic acid, please contact our sales team through the website or via email, providing your contact details and quantity requirements.
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