2-Fluorophenylzinc iodide solution
2-Fluorophenylzinc iodide solution (CAS: 186000-41-9, FC6H4ZnI) is a versatile organozinc reagent supplied by Tech Serve Solutions. With a molecular weight of 287.39 g/mol and supplied as a 0.5 M solution in THF, it is primarily utilised in organic synthesis for the formation of carbon-carbon bonds. This reagent is instrumental in cross-coupling reactions, enabling the introduction of the 2-fluorophenyl group into complex molecular architectures. Its application is crucial in the synthesis of pharmaceuticals and advanced materials.
Cross-Coupling Reactions
2-Fluorophenylzinc iodide solution is a key reagent in palladium-catalysed cross-coupling reactions, such as Negishi coupling. It facilitates the formation of C-C bonds by transferring the 2-fluorophenyl group to various organic electrophiles.
Synthesis of Fluorinated Aromatics
This organozinc compound serves as a valuable building block for constructing complex molecules containing the 2-fluorophenyl moiety. These structures are often found in pharmaceuticals and agrochemicals.
Organometallic Chemistry
As an organozinc halide, it is a significant tool in organometallic chemistry, allowing for precise functionalization and modification of organic frameworks through its reactivity.
| Molecular weight | 287.39 |
|---|---|
| Linear formula | FC6H4ZnI |
| Boiling point | 65 °C |
| Density | 1.03 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluorophenylzinc iodide solution used for?
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2-Fluorophenylzinc iodide solution is primarily used in organic synthesis for cross-coupling reactions and the construction of fluorinated aromatic compounds. It enables the efficient introduction of the 2-fluorophenyl group into various molecular structures.
What is the CAS number and chemical formula for 2-Fluorophenylzinc iodide solution?
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The CAS number is 186000-41-9 and the linear chemical formula is FC6H4ZnI.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluorophenylzinc iodide solution at a concentration of 0.5 M in THF. This is a technical grade reagent suitable for research and chemical synthesis. Tech Serve Solutions does not represent this product as USP, BP, or EP grade.
How should 2-Fluorophenylzinc iodide solution be handled safely?
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This product is highly flammable (H225) and can cause serious eye irritation (H319) and respiratory irritation (H335). It is suspected of causing cancer (H351) and may form explosive peroxides. Handle in a well-ventilated area, away from ignition sources, using appropriate personal protective equipment. Store at 2-8°C.
How is 2-Fluorophenylzinc iodide solution packed, shipped, and exported?
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2-Fluorophenylzinc iodide solution is shipped as a flammable liquid (UN 2056, Class 3, Packing Group II) under controlled temperature conditions (2-8°C) to maintain its stability and reactivity. Tech Serve Solutions is an experienced global exporter of fine chemicals.
How can I request a sample or quote for 2-Fluorophenylzinc iodide solution?
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To request a sample or a quote, please contact our sales department through the website or via email, specifying the product name and CAS number (186000-41-9).
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