2-(Difluoromethoxy)benzaldehyde
2-(Difluoromethoxy)benzaldehyde (CAS: 71653-64-0) is a fluorinated organic building block with the linear formula F₂HOCC₆H₄CHO and a molecular weight of 172.13 g/mol. This aldehyde is characterised by its difluoromethoxy substituent, making it a valuable intermediate in organic synthesis. It is primarily utilised in the development of novel pharmaceutical compounds and advanced materials where fluorination imparts unique chemical and physical properties.

Pharmaceutical Intermediate
Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), leveraging the influence of the difluoromethoxy group on drug efficacy and metabolic stability.
Agrochemical Synthesis
Incorporated into the development of new agrochemicals, contributing to the creation of compounds with enhanced biological activity and environmental profiles.
Materials Science
Used in the synthesis of specialised polymers and functional materials where the unique electronic and physical properties conferred by the fluorinated moiety are desirable.
Organic Synthesis
A versatile reagent for introducing the difluoromethoxyphenyl group into complex organic molecules, facilitating diverse synthetic transformations.
| Molecular weight | 172.13 |
|---|---|
| Linear formula | F2CHOC6H4CHO |
| Assay | 97% |
| Boiling point | 216 °C(lit.) |
| Density | 1.3 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.497(lit.) |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Flash point | 107 °C / 224.6 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Difluoromethoxy)benzaldehyde used for?
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2-(Difluoromethoxy)benzaldehyde is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals, agrochemicals, and advanced materials due to its difluoromethoxy substituent.
What is the CAS number and chemical formula for 2-(Difluoromethoxy)benzaldehyde?
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The CAS number is 71653-64-0 and the linear formula is F₂HOCC₆H₄CHO.
What grade and purity does Tech Serve Solutions supply for 2-(Difluoromethoxy)benzaldehyde?
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Tech Serve Solutions supplies 2-(Difluoromethoxy)benzaldehyde with an assay of 97%. This product is suitable for research and general chemical synthesis; it is not supplied as USP, BP, or EP grade.
What are the main safety hazards associated with 2-(Difluoromethoxy)benzaldehyde?
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2-(Difluoromethoxy)benzaldehyde is a combustible liquid with a flash point of 107 °C (224.6 °F). It requires handling with appropriate personal protective equipment, including eyeshields and gloves, and should be kept away from heat and ignition sources. It is classified under WGK Germany 3.
How is 2-(Difluoromethoxy)benzaldehyde supplied and exported by TSS?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-(Difluoromethoxy)benzaldehyde, which can be packed and shipped according to international standards for chemical export.
How can I request a quote or sample for 2-(Difluoromethoxy)benzaldehyde?
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To request a quote or sample of 2-(Difluoromethoxy)benzaldehyde, please contact our sales team through the TSS website or via the provided contact details.
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