2-Chloro-5-fluoro-pyridin-3-ol
2-Chloro-5-fluoro-pyridin-3-ol (CAS: 884494-35-3) is a heterocyclic organic compound with the molecular formula C5H3ClFNO and a molecular weight of 147.53 g/mol. As a fluorinated pyridine derivative, it serves as a valuable building block in complex chemical synthesis. Its structure lends itself to incorporation into various molecular frameworks, particularly in the development of novel chemical entities for research and industrial applications.

Organic Synthesis Intermediate
This compound functions as a key intermediate in the synthesis of more complex organic molecules. Its halogenated and hydroxylated pyridine core allows for diverse functionalisation and coupling reactions.
Pharmaceutical Research
The presence of fluorine and the pyridine ring makes 2-Chloro-5-fluoro-pyridin-3-ol a useful synthon in medicinal chemistry for developing potential drug candidates. Fluorine substitution can favourably alter pharmacokinetic properties.
Agrochemical Development
It can be utilised in the discovery and synthesis of new agrochemicals, such as pesticides or herbicides, where heterocyclic structures are often employed for biological activity.
Materials Science
The unique electronic and structural properties of fluorinated heterocycles may find applications in the development of advanced materials with specific functionalities.
| Molecular weight | 147.53 |
|---|---|
| Empirical formula | C5H3ClFNO |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Flash point | 100 °C / 212 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-5-fluoro-pyridin-3-ol used for?
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2-Chloro-5-fluoro-pyridin-3-ol is primarily used as a building block and intermediate in organic synthesis, particularly for pharmaceutical and agrochemical research and development.
What is the CAS number and formula for 2-Chloro-5-fluoro-pyridin-3-ol?
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The CAS number is 884494-35-3 and the empirical formula is C5H3ClFNO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research and development purposes. The specific assay and grade are available upon request and documented on the Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
How should 2-Chloro-5-fluoro-pyridin-3-ol be handled?
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This compound is classified as Dangerous. It is harmful if swallowed, causes skin irritation, causes serious eye damage, and may cause respiratory irritation. Always handle with appropriate personal protective equipment in a well-ventilated area, avoiding contact with skin, eyes, and clothing. Refer to the Safety Data Sheet (SDS) for detailed handling and safety information.
Is 2-Chloro-5-fluoro-pyridin-3-ol controlled or scheduled?
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The provided data does not indicate that 2-Chloro-5-fluoro-pyridin-3-ol is a controlled or scheduled substance.
How is 2-Chloro-5-fluoro-pyridin-3-ol packed and exported?
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Tech Serve Solutions exports fine chemicals globally, ensuring appropriate packaging for safe transport in compliance with international shipping regulations. Detailed shipping information is available upon inquiry.
How can I request a sample or quote for 2-Chloro-5-fluoro-pyridin-3-ol?
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To request a sample or a quotation, please contact our sales department via the website or directly by email, providing your specific requirements and shipping details.
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