2-Chloro-4-fluorobenzenesulfonyl chloride
2-Chloro-4-fluorobenzenesulfonyl chloride (CAS: 85958-57-2; Formula: C6H3Cl2FO2S; Molar Mass: 229.06 g/mol) is a reactive sulfonyl chloride intermediate. This compound serves as a valuable building block in organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals. Its structure, featuring both chloro and fluoro substituents on the benzene ring, offers unique reactivity for diverse chemical transformations. Available from Tech Serve Solutions at 95% purity.

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. The compound's functional groups allow for the introduction of specific pharmacophores into complex molecular structures.
Agrochemical Synthesis
Serves as a key intermediate in the production of pesticides, herbicides, and fungicides. Its incorporation can lead to molecules with enhanced biological activity and targeted pest control properties.
Material Science
Explored for the development of novel functional materials. Its reactivity can be leveraged to create polymers or specialized organic compounds with desired electronic or physical properties.
Research and Development
A versatile building block for academic and industrial research laboratories exploring new synthetic routes and chemical entities. Facilitates the creation of diverse libraries for drug discovery and chemical research.
| Molecular weight | 229.06 |
|---|---|
| Empirical formula | C6H3Cl2FO2S |
| Assay | 95% |
| Boiling point | 243-244 °C(lit.) |
| Density | 1.569 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5550(lit.) |
| Melting point | 27-31 °C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3265 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-4-fluorobenzenesulfonyl chloride used for?
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2-Chloro-4-fluorobenzenesulfonyl chloride is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals, agrochemicals, and novel materials. It is also widely employed in research and development laboratories.
What are the CAS number and chemical formula for 2-Chloro-4-fluorobenzenesulfonyl chloride?
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The CAS number is 85958-57-2 and the chemical formula is C6H3Cl2FO2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-4-fluorobenzenesulfonyl chloride with a purity of 95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Chloro-4-fluorobenzenesulfonyl chloride be handled safely?
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2-Chloro-4-fluorobenzenesulfonyl chloride is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Handling requires full personal protective equipment including gloves, goggles, a face shield, and appropriate respiratory protection. It is crucial to avoid contact with skin, eyes, and clothing. Refer to the Safety Data Sheet for detailed handling and emergency procedures.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions carefully packs and prepares chemicals for safe transport, adhering to all international shipping regulations. We are experienced global exporters of fine chemicals and laboratory reagents.
How can I request a quote or sample for 2-Chloro-4-fluorobenzenesulfonyl chloride?
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To request a quote or a sample, please contact our sales team through the website or by calling us. Provide the product name and CAS number for prompt service.
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