2-Chloro-4-fluoroanisole
2-Chloro-4-fluoroanisole (CAS: 2267-25-6), with the molecular formula ClC6H3(F)OCH3 and a molecular weight of 160.57 g/mol, is a halogenated aromatic ether. It serves as a versatile intermediate in organic synthesis. Its structure, featuring both chlorine and fluorine substituents alongside a methoxy group on a benzene ring, makes it valuable for introducing specific functionalities in the preparation of more complex organic molecules, particularly within the pharmaceutical and agrochemical sectors.
Organic Synthesis Intermediate
2-Chloro-4-fluoroanisole is employed as a key building block in multi-step organic syntheses. Its reactive sites allow for diverse chemical transformations, enabling the construction of novel molecular architectures.
Pharmaceutical Research
This compound is utilised in the development of new pharmaceutical agents. Its fluorinated and chlorinated aromatic structure can impart desirable pharmacokinetic properties to drug candidates.
Agrochemical Development
It serves as a precursor in the synthesis of active ingredients for agrochemicals. The specific substitution pattern can contribute to the efficacy and selectivity of pesticides and herbicides.
Material Science
As a specialised organic building block, it may find applications in the synthesis of advanced materials where precise control over electronic or physical properties is required.
| Molecular weight | 160.57 |
|---|---|
| Linear formula | ClC6H3(F)OCH3 |
| Assay | 97% |
| Boiling point | 197-200 °C(lit.) |
| Density | 1.29 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.519(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 76 °C / 168.8 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-4-fluoroanisole used for?
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2-Chloro-4-fluoroanisole is primarily used as an intermediate in organic synthesis, particularly in the research and development of pharmaceuticals and agrochemicals.
What is the CAS number and molecular formula for 2-Chloro-4-fluoroanisole?
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The CAS number for 2-Chloro-4-fluoroanisole is 2267-25-6, and its molecular formula is ClC6H3(F)OCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-4-fluoroanisole with an assay of 97%. This product is intended for research and chemical synthesis purposes; TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling precautions for 2-Chloro-4-fluoroanisole?
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2-Chloro-4-fluoroanisole is classified as a Warning, with hazard statements H315, H319, and H335, indicating it causes skin irritation, serious eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection (e.g., type ABEK respirator filter), should be used. Handle in a well-ventilated area.
How is 2-Chloro-4-fluoroanisole packed and shipped by TSS?
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Tech Serve Solutions exports 2-Chloro-4-fluoroanisole in compliance with relevant shipping regulations. Packaging is designed to ensure product integrity during transit. Please contact us for specific shipping and export details.
How can I request a sample or quote for 2-Chloro-4-fluoroanisole?
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To request a sample or a quote for 2-Chloro-4-fluoroanisole, please use the contact form on our website or reach out to our sales team directly.
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