2,5-Difluorobenzylamine
2,5-Difluorobenzylamine (CAS: 85118-06-5) is a fluorinated organic building block with the linear formula F2C6H3CH2NH2 and a molecular weight of 143.13 g/mol. This compound is primarily utilised as a key intermediate in chemical synthesis. Its difluorinated aromatic structure makes it valuable for introducing specific fluorine-containing moieties into larger molecules, particularly in the development of novel compounds within pharmaceutical research and material science.
- Synonyms
- F2C6H3CH2NH2
Amine Building Block in Tandem Reactions
2,5-Difluorobenzylamine serves as an amine building block in tandem Ugi/Diels-Alder reactions. This application has been specifically demonstrated on soluble polymer supports, facilitating complex molecule synthesis.
Fluorinated Intermediate in Organic Synthesis
As a fluorinated aryl compound, it is employed as a versatile intermediate in the synthesis of more complex organic molecules. The presence of two fluorine atoms can influence the electronic properties and metabolic stability of target compounds.
Research and Development
This compound is utilised in academic and industrial research laboratories for exploring new synthetic pathways and developing novel chemical entities. Its unique structure allows for diverse functionalisation.
| Molecular weight | 143.13 |
|---|---|
| Linear formula | F2C6H3CH2NH2 |
| Assay | 97% |
| Density | 1.222 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.495(lit.) |
| Application | 2,5-Difluorobenzylamine has been used as amine building block in tandem Ugi/Diels-Alder reaction on soluble polymer support1. |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 76 °C / 168.8 °F |
| Transport (UN / ADR) | UN 2735 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Difluorobenzylamine used for?
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2,5-Difluorobenzylamine is used as an amine building block in tandem Ugi/Diels-Alder reactions and as a general intermediate in organic synthesis for introducing fluorinated moieties into target molecules.
What is the CAS number and formula for 2,5-Difluorobenzylamine?
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The CAS number for 2,5-Difluorobenzylamine is 85118-06-5, and its linear formula is F2C6H3CH2NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,5-Difluorobenzylamine with an assay of 97%. This product is typically considered for research or technical use; TSS does not represent it as USP, BP, or EP grade.
How should 2,5-Difluorobenzylamine be handled safely?
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2,5-Difluorobenzylamine is a corrosive substance (H314). Handling requires appropriate personal protective equipment, including chemical-resistant gloves, eye protection (goggles and face shield), and respiratory protection. Ensure adequate ventilation and avoid contact with skin, eyes, and clothing.
Is 2,5-Difluorobenzylamine packed and shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2,5-Difluorobenzylamine, adhering to international shipping regulations (UN 2735, Class 8).
How can I request a quote or sample for 2,5-Difluorobenzylamine?
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To request a quote or a sample of 2,5-Difluorobenzylamine, please contact our sales department through the website or by phone.
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