2,2,2-Trifluoro-2′,4′-dimethoxyacetophenone
2,2,2-Trifluoro-2′,4′-dimethoxyacetophenone (CAS 578-16-5) is a specialized organic compound with the linear formula (CH3O)2C6H3COCF3 and a molecular weight of 234.17 g/mol. It serves as a valuable building block in chemical synthesis, particularly within the realm of carbonyl compounds and ketones. Its unique trifluoromethyl ketone structure makes it useful for introducing fluorinated moieties into more complex molecules, facilitating research and development in various chemical fields.
- Synonyms
- 4 -dimethoxyacetophenone578-16-5(CH3O)2C6H3COCF3

Organic Synthesis Intermediate
This compound functions as a key intermediate in the synthesis of more complex organic molecules. Its trifluoromethyl ketone group offers unique reactivity for various synthetic transformations.
Fluorinated Compound Development
Utilised in research and development for creating novel fluorinated compounds. The presence of the CF3 group can significantly alter the properties of target molecules, impacting factors like lipophilicity and metabolic stability.
Research Chemical
A valuable reagent for academic and industrial research laboratories exploring new chemical pathways and developing novel materials or pharmaceutical candidates.
| Molecular weight | 234.17 |
|---|---|
| Linear formula | (CH3O)2C6H3COCF3 |
| Assay | 95% |
| Melting point | 48-52 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2,2-Trifluoro-2′,4′-dimethoxyacetophenone used for?
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2,2,2-Trifluoro-2′,4′-dimethoxyacetophenone is primarily used as an intermediate in organic synthesis and for the development of novel fluorinated compounds in research settings.
What are the CAS number and formula for this compound?
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The CAS number is 578-16-5 and the linear formula is (CH3O)2C6H3COCF3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at an assay of 95%. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling recommendations for 578-16-5?
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According to safety data, appropriate personal protective equipment includes eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound is classified under WGK Germany 3, indicating a high hazard to water.
How is 2,2,2-Trifluoro-2′,4′-dimethoxyacetophenone packed, shipped, and exported?
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Tech Serve Solutions carefully packs and ships chemicals in compliance with all international regulations for hazardous materials. We are experienced global exporters.
How can I request a sample or a quote for 2,2,2-Trifluoro-2′,4′-dimethoxyacetophenone?
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To request a sample or a quote, please contact our sales department via the website or direct email, providing your specific requirements and shipping details.
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