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(1R,2S)-(−)-Ephedrine nitrate

CAS 81012-98-8C6H5CH[CH(NHCH3)CH3]OH·HNO3Chemical Synthesis

(1R,2S)-(−)-Ephedrine nitrate (CAS: 81012-98-8) is a chiral organic compound with the molecular formula C6H5CH[CH(NHCH3)CH3]OH·HNO3 and a molecular weight of 228.25 g/mol. As an ephedrine derivative, it serves as a valuable chiral auxiliary in asymmetric synthesis and chemical reactions. Its optical activity and specific stereochemistry make it suitable for enantioselective processes.

IUPAC
(1R,2S)-(−)-α-(1-Methylaminoethyl)benzyl alcohol nitrate
Synonyms
C6H5CH[CH(NHCH3)CH3]OH·HNO3(1R,2S)-(−)-α-(1-Methylaminoethyl)benzyl alcohol nitrate
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(1R,2S)-(−)-Ephedrine nitrate (C6H5CH[CH(NHCH3)CH3]OH·HNO3) — chemical structure, CAS 81012-98-8; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral AuxiliariesEphedrine Derivatives
01 /Applications

Chiral Auxiliary in Asymmetric Synthesis

This compound functions as a chiral auxiliary, guiding stereoselective reactions to produce enantiomerically enriched products. It is instrumental in establishing specific stereocenters during complex organic syntheses.

Reagent in Chemical Synthesis

It is employed as a reagent in various chemical transformations where chirality is a critical factor. Its defined stereochemistry allows for precise control over reaction outcomes.

Research and Development

Utilised in research laboratories for exploring new synthetic methodologies and developing novel chiral molecules. Its properties are of interest in medicinal chemistry and materials science.

02 /Properties
Molecular weight228.25
Linear formulaC6H5CH[CH(NHCH3)CH3]OH·HNO3
Assay99%
Optical activity[α]21/D −31°, c = 5 in H2O
Melting point126-128 °C(lit.)
03 /Identifiers & registry
CAS number
81012-98-8
MDL number
MFCD00012627
PubChem substance
24888507
04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is (1R,2S)-(−)-Ephedrine nitrate used for?

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(1R,2S)-(−)-Ephedrine nitrate is primarily used as a chiral auxiliary in asymmetric synthesis and as a reagent in chemical synthesis where stereochemical control is important. It is also utilised in research and development for exploring new synthetic methodologies.

What are the CAS number and formula for (1R,2S)-(−)-Ephedrine nitrate?

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The CAS number for (1R,2S)-(−)-Ephedrine nitrate is 81012-98-8. Its linear formula is C6H5CH[CH(NHCH3)CH3]OH·HNO3.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (1R,2S)-(−)-Ephedrine nitrate with an assay of 99%. We do not represent this product as USP, BP, or EP grade.

How should (1R,2S)-(−)-Ephedrine nitrate be handled?

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(1R,2S)-(−)-Ephedrine nitrate is classified under WGK 2 in Germany, indicating it is hazardous to water. Appropriate personal protective equipment should be used, and handling should occur in a well-ventilated area, avoiding release into the environment.

Is (1R,2S)-(−)-Ephedrine nitrate a controlled substance?

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Information regarding the controlled substance status of (1R,2S)-(−)-Ephedrine nitrate is not provided in the available data. Customers should verify its regulatory status in their specific jurisdiction.

How is (1R,2S)-(−)-Ephedrine nitrate packed and shipped?

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Tech Serve Solutions exports chemicals globally. Specific packing and shipping details are determined by order volume, destination, and regulatory requirements. Please contact us for detailed information.

How can I request a sample or quote for (1R,2S)-(−)-Ephedrine nitrate?

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To request a sample or quote for (1R,2S)-(−)-Ephedrine nitrate, please use the contact form on our website or contact our sales department directly. Please include the CAS number 81012-98-8 in your request.

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