1-(Trimethylsilyl)-2-pyrrolidinone
1-(Trimethylsilyl)-2-pyrrolidinone (CAS: 14468-90-7), with the empirical formula C7H15NOSi and a molecular weight of 157.29 g/mol, is a heterocyclic organic compound. It serves as a valuable intermediate and building block in organic synthesis. Its structure, featuring a silyl group attached to a pyrrolidinone ring, allows for diverse chemical transformations, making it useful in the development of novel materials and complex molecules.

Organic Synthesis Intermediate
This compound functions as a key intermediate in multi-step organic syntheses. Its silyl and lactam functionalities enable selective reactions and the construction of more complex molecular architectures.
Heterocyclic Chemistry Building Block
As a pyrrolidine derivative, it is employed as a versatile building block in the synthesis of various heterocyclic compounds with potential applications in pharmaceuticals and materials science.
Reagent in Derivatization
The trimethylsilyl group can be used to introduce a labile protecting group or to facilitate specific reactions, acting as a derivatization reagent in specialized chemical processes.
| Molecular weight | 157.29 |
|---|---|
| Empirical formula | C7H15NOSi |
| Assay | 96% |
| Boiling point | 90 °C/20 mmHg(lit.) |
| Density | 0.983 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.46(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 53 °C / 127.4 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(Trimethylsilyl)-2-pyrrolidinone used for?
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1-(Trimethylsilyl)-2-pyrrolidinone is primarily used as an intermediate and building block in organic synthesis, particularly in the construction of heterocyclic compounds.
What is the CAS number and formula for 1-(Trimethylsilyl)-2-pyrrolidinone?
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The CAS number is 14468-90-7 and the empirical formula is C7H15NOSi.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(Trimethylsilyl)-2-pyrrolidinone with an assay of 96%. It is supplied as a technical or research grade chemical, and TSS does not represent it as USP, BP, or EP grade.
How should 1-(Trimethylsilyl)-2-pyrrolidinone be handled safely?
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1-(Trimethylsilyl)-2-pyrrolidinone is a flammable liquid and vapour (H226) and can cause skin (H315), serious eye (H319), and respiratory irritation (H335). Handle in a well-ventilated area, away from ignition sources, wearing appropriate personal protective equipment including eyeshields, gloves, and a suitable respirator.
How is 1-(Trimethylsilyl)-2-pyrrolidinone packed, shipped, and exported?
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1-(Trimethylsilyl)-2-pyrrolidinone is packed, shipped, and exported in compliance with all relevant transport regulations for hazardous materials, including UN 1993 classification.
How can I request a quote or sample for 1-(Trimethylsilyl)-2-pyrrolidinone?
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To request a quote or sample, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels.
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