1-(p-Toluenesulfonyl)imidazole
1-(p-Toluenesulfonyl)imidazole (CAS: 2232-08-8; Formula: C10H10N2O2S; MW: 222.26 g/mol) is a versatile organic compound widely utilised as a building block in chemical synthesis. It serves as a key reagent for tosylation reactions, introducing the tosyl group into various organic molecules. Its imidazole core and sulfonyl functionality make it valuable in the preparation of pharmaceuticals and other complex organic structures.
- IUPAC
- 1-Tosylimidazole
- Synonyms
- 1-Tosylimidazole
Tosylation Reagent
This compound is primarily employed as a tosylating agent. It efficiently transfers the p-toluenesulfonyl (tosyl) group to nucleophiles such as alcohols and amines, facilitating the formation of tosylate esters and sulfonamides.
Organic Synthesis Intermediate
1-(p-Toluenesulfonyl)imidazole acts as a crucial intermediate in the construction of complex organic molecules. Its reactivity allows for the introduction of specific functionalities required in multi-step synthetic pathways.
Heterocyclic Chemistry
As a derivative of imidazole, it finds applications in the synthesis of various heterocyclic compounds. These structures are often found in biologically active molecules and advanced materials.
| Molecular weight | 222.26 |
|---|---|
| Empirical formula | C10H10N2O2S |
| Assay | ≥98.0% (S) |
| Melting point | 76-78 °C(lit.)76-78 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(p-Toluenesulfonyl)imidazole used for?
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1-(p-Toluenesulfonyl)imidazole is primarily used as a tosylation reagent in organic synthesis and as an intermediate for constructing complex organic molecules and heterocyclic compounds.
What are the CAS number and molecular formula for 1-(p-Toluenesulfonyl)imidazole?
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The CAS number for 1-(p-Toluenesulfonyl)imidazole is 2232-08-8, and its molecular formula is C10H10N2O2S.
What grade and purity does Tech Serve Solutions supply for 1-(p-Toluenesulfonyl)imidazole?
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Tech Serve Solutions supplies 1-(p-Toluenesulfonyl)imidazole with an assay of ≥98.0% (S). We do not represent this product as USP, BP, or EP grade.
What are the main hazards associated with 1-(p-Toluenesulfonyl)imidazole?
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1-(p-Toluenesulfonyl)imidazole is classified with GHS07 symbol and a Warning signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves.
Is 1-(p-Toluenesulfonyl)imidazole available for export from TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 1-(p-Toluenesulfonyl)imidazole.
How can I request a sample or a quote for 1-(p-Toluenesulfonyl)imidazole?
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To request a sample or a quote for 1-(p-Toluenesulfonyl)imidazole, please contact our sales team through the website or by calling us.
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