1-Acetyl-1H-1,2,3-triazolo[4,5-b]pyridine
1-Acetyl-1H-1,2,3-triazolo[4,5-b]pyridine (CAS 107866-54-6) is a heterocyclic organic compound with the molecular formula C7H6N4O and a molecular weight of 162.15 g/mol. This compound serves as a valuable reactant in various synthetic organic chemistry applications. Its specific utility includes solid-phase synthesis of carpanone-based inhibitors, preparation of selective cyclooxygenase-2 (COX-2) inactivators, and the acetylation of amines, underscoring its role in complex molecule construction.
- Synonyms
- 5-b]pyridine,107866-54-6, C7H6N4O
![1-Acetyl-1H-1,2,3-triazolo[4,5-b]pyridine (C7H6N4O) — chemical structure, CAS 107866-54-6; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F107866-54-6.png&w=3840&q=75)
Solid-Phase Synthesis
Utilised as a reactant in solid-phase synthesis for creating carpanone-based inhibitors of exocytosis originating from the Golgi apparatus.
Preparation of COX-2 Inactivators
Employed in the preparation of selective cyclooxygenase-2 (COX-2) inactivators, crucial in medicinal chemistry research.
Acetylation of Amines
Serves as an acetylating agent for amines, a fundamental transformation in organic synthesis for modifying molecular structures.
| Molecular weight | 162.15 |
|---|---|
| Empirical formula | C7H6N4O |
| Assay | 97% |
| Application | Reactant for:• Solid-phase synthesis of carpanone-based inhibitors of exocytosis from Golgi apparatus1• Preparation selective cyclooxygenase-2 (COX-2) inactivators2• Acetylation of amines3 |
| Melting point | 116-118 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Acetyl-1H-1,2,3-triazolo[4,5-b]pyridine used for?
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It is used as a reactant in solid-phase synthesis of carpanone-based inhibitors of exocytosis, preparation of selective cyclooxygenase-2 (COX-2) inactivators, and for the acetylation of amines.
What is the CAS number and chemical formula for this compound?
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The CAS number is 107866-54-6 and the empirical formula is C7H6N4O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound at an assay of 97%. It is typically considered a research or technical grade material, and is not supplied as USP, BP, or EP.
What are the safety and handling considerations for 1-Acetyl-1H-1,2,3-triazolo[4,5-b]pyridine?
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This compound is classified as a Warning (GHS07) and is associated with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Recommended personal protective equipment includes a dust mask type N95, eyeshields, and gloves. Handle in a well-ventilated area and avoid breathing dust.
How is 1-Acetyl-1H-1,2,3-triazolo[4,5-b]pyridine packed and shipped?
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Products are carefully packed according to international regulations for export and shipping. Specific packaging details can be provided upon request.
How can I request a quote or sample?
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To request a quote or a sample, please use the contact form on our website or email our sales department directly with your inquiry.
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